PROK1_HUMAN   P58294


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UniProt:P58294

Recommended name:Prokineticin-1

EC number:

Alternative names:(Endocrine-gland-derived vascular endothelial growth factor) (EG-VEGF) (Mambakine)

Cleaved into:

GeneID:84432

Gene names  (primary ):PROK1

Gene names  (synonym ):

Gene names  (ORF ):UNQ600/PRO1186

Length:105

Mass:11715

Sequence:MRGATRVSIMLLLVTVSDCAVITGACERDVQCGAGTCCAISLWLRGLRMCTPLGREGEECHPGSHKVPFFRKRKHHTCPCLPNLLCSRFPDGRYRCSMDLKNINF

Tissue specificity:Localizes to glandular epithelium, stroma and vascular epithelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the steroidogenic glands, ovary, testis, adrenal and placenta. {ECO:0000269|PubMed:11528470, ECO:0000269|PubMed:15292351, ECO:0000269|PubMed:18339712}.

Induction:

Developmental stage:In adult testis, is strongly expressed only in Leydig cells. In testicular tumors, expressed specifically in Leydig cell tumors (at protein level). Expressed from 14 weeks until birth in fetal testis.

Protein families:AVIT (prokineticin) family


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