PROK1_HUMAN P58294
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UniProt:P58294
Recommended name:Prokineticin-1
EC number:
Alternative names:(Endocrine-gland-derived vascular endothelial growth factor) (EG-VEGF) (Mambakine)
Cleaved into:
GeneID:84432
Gene names (primary ):PROK1
Gene names (synonym ):
Gene names (ORF ):UNQ600/PRO1186
Length:105
Mass:11715
Sequence:MRGATRVSIMLLLVTVSDCAVITGACERDVQCGAGTCCAISLWLRGLRMCTPLGREGEECHPGSHKVPFFRKRKHHTCPCLPNLLCSRFPDGRYRCSMDLKNINF
Tissue specificity:Localizes to glandular epithelium, stroma and vascular epithelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the steroidogenic glands, ovary, testis, adrenal and placenta. {ECO:0000269|PubMed:11528470, ECO:0000269|PubMed:15292351, ECO:0000269|PubMed:18339712}.
Induction:
Developmental stage:In adult testis, is strongly expressed only in Leydig cells. In testicular tumors, expressed specifically in Leydig cell tumors (at protein level). Expressed from 14 weeks until birth in fetal testis.
Protein families:AVIT (prokineticin) family