SDF1_HUMAN P48061
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UniProt:P48061
Recommended name：Stromal cell-derived factor 1
EC number：
Alternative names：(SDF-1) (hSDF-1) (C-X-C motif chemokine 12) (Intercrine reduced in hepatomas) (IRH) (hIRH) (Pre-B cell growth-stimulating factor) (PBSF)
Cleaved into：SDF-1-beta(3-72); SDF-1-alpha(3-67)
GeneID：6387
Gene names (primary )：CXCL12
Gene names (synonym )：SDF1 SDF1A SDF1B
Gene names (ORF )：
Length：93
Mass：10666
Sequence：MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIVARLKNNNRQVCIDPKLKWIQEYLEKALNKRFKM
Tissue specificity：Isoform Alpha and isoform Beta are ubiquitously expressed, with highest levels detected in liver, pancreas and spleen. Isoform Gamma is mainly expressed in heart, with weak expression detected in several other tissues. Isoform Delta, isoform Epsilon and isoform Theta have highest expression levels in pancreas, with lower levels detected in heart, kidney, liver and spleen. {ECO:0000269|PubMed:16626895}.
Induction：
Developmental stage：Isoform Alpha is ubiquitously expressed in fetal tissues. Isoform Beta and isoform Delta have more limited expression patterns, with highest levels detected in fetal spleen and fetal liver, respectively. Isoform Gamma and isoform Theta are weakly detected in fetal kidney. {ECO:0000269|PubMed:16626895}.
Protein families：Intercrine alpha (chemokine CxC) family