PRG2_HUMAN P13727
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UniProt:P13727
Recommended name:Bone marrow proteoglycan
EC number:
Alternative names:(BMPG) (Proteoglycan 2)
Cleaved into:Eosinophil granule major basic protein (EMBP) (MBP) (Pregnancy-associated major basic protein)
GeneID:5553
Gene names (primary ):PRG2
Gene names (synonym ):MBP
Gene names (ORF ):
Length:222
Mass:25206
Sequence:MKLPLLLALLFGAVSALHLRSETSTFETPLGAKTLPEDEETPEQEMEETPCRELEEEEEWGSGSEDASKKDGAVESISVPDMVDKNLTCPEEEDTVKVVGIPGCQTCRYLLVRSLQTFSQAWFTCRRCYRGNLVSIHNFNINYRIQCSVSALNQGQVWIGGRITGSGRCRRFQWVDGSRWNFAYWAAHQPWSRGGHCVALCTRGGHWRRAHCLRRLPFICSY
Tissue specificity:High levels of the proform in placenta and pregnancy serum; in placenta, localized to X cells of septa and anchoring villi. Lower levels in a variety of other tissues including kidney, myometrium, endometrium, ovaries, breast, prostate, bone marrow and colon. {ECO:0000269|PubMed:10491647, ECO:0000269|PubMed:7526035}.
Induction:
Developmental stage:Levels of the proform increase in serum and placenta during pregnancy. {ECO:0000269|PubMed:10491647, ECO:0000269|PubMed:7539791}.
Protein families: