PRG2_HUMAN   P13727


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UniProt:P13727

Recommended name:Bone marrow proteoglycan

EC number:

Alternative names:(BMPG) (Proteoglycan 2)

Cleaved into:Eosinophil granule major basic protein (EMBP) (MBP) (Pregnancy-associated major basic protein)

GeneID:5553

Gene names  (primary ):PRG2

Gene names  (synonym ):MBP

Gene names  (ORF ):

Length:222

Mass:25206

Sequence:MKLPLLLALLFGAVSALHLRSETSTFETPLGAKTLPEDEETPEQEMEETPCRELEEEEEWGSGSEDASKKDGAVESISVPDMVDKNLTCPEEEDTVKVVGIPGCQTCRYLLVRSLQTFSQAWFTCRRCYRGNLVSIHNFNINYRIQCSVSALNQGQVWIGGRITGSGRCRRFQWVDGSRWNFAYWAAHQPWSRGGHCVALCTRGGHWRRAHCLRRLPFICSY

Tissue specificity:High levels of the proform in placenta and pregnancy serum; in placenta, localized to X cells of septa and anchoring villi. Lower levels in a variety of other tissues including kidney, myometrium, endometrium, ovaries, breast, prostate, bone marrow and colon. {ECO:0000269|PubMed:10491647, ECO:0000269|PubMed:7526035}.

Induction:

Developmental stage:Levels of the proform increase in serum and placenta during pregnancy. {ECO:0000269|PubMed:10491647, ECO:0000269|PubMed:7539791}.

Protein families:


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