KMT5A_HUMAN Q9NQR1
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UniProt:Q9NQR1
Recommended name：N-lysine methyltransferase KMT5A
EC number：EC:2.1.1.-
Alternative names：(H4-K20-HMTase KMT5A) (Histone-lysine N-methyltransferase KMT5A) (Lysine N-methyltransferase 5A) (Lysine-specific methylase 5A) (PR/SET domain-containing protein 07) (PR-Set7) (PR/SET07) (SET domain-containing protein 8)
Cleaved into：
GeneID：387893
Gene names (primary )：KMT5A
Gene names (synonym )：PRSET7 SET07 SET8 SETD8
Gene names (ORF )：
Length：393
Mass：42890
Sequence：MGEGGAAAALVAAAAAAAAAAAAVVAGQRRRRLGRRARCHGPGRAAGGKMSKPCAVEAAAAAVAATAPGPEMVERRGPGRPRTDGENVFTGQSKIYSYMSPNKCSGMRFPLQEENSVTHHEVKCQGKPLAGIYRKREEKRNAGNAVRSAMKSEEQKIKDARKGPLVPFPNQKSEAAEPPKTPPSSCDSTNAAIAKQALKKPIKGKQAPRKKAQGKTQQNRKLTDFYPVRRSSRKSKAELQSEERKRIDELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDYGDRSKASIEAHPWLKH
Tissue specificity：
Induction：By HCFC1 C-terminal chain, independently of HCFC1 N-terminal chain. Transiently induced by TGF-beta and during the cell cycle. {ECO:0000269|PubMed:15200950, ECO:0000269|PubMed:23478445}.
Developmental stage：Not detected during G1 phase. First detected during S through G2 phases, and peaks during mitosis (at protein level). {ECO:0000269|PubMed:12208845}.
Protein families：Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, PR/SET subfamily