NDRG2_HUMAN Q9UN36
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UniProt:Q9UN36
Recommended name：Protein NDRG2
EC number：
Alternative names：(N-myc downstream-regulated gene 2 protein) (Protein Syld709613)
Cleaved into：
GeneID：57447
Gene names (primary )：NDRG2
Gene names (synonym )：KIAA1248 SYLD
Gene names (ORF )：
Length：371
Mass：40798
Sequence：MAELQEVQITEEKPLLPGQTPEAAKEAELAARILLDQGQTHSVETPYGSVTFTVYGTPKPKRPAILTYHDVGLNYKSCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCVLQYLNFSTIIGVGVGAGAYILARYALNHPDTVEGLVLINIDPNAKGWMDWAAHKLTGLTSSIPEMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWNSYNNRRDLNFERGGDITLRCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQLTQPGKLTEAFKYFLQGMGYMASSCMTRLSRSRTASLTSAASVDGNRSRSRTLSQSSESGTLSSGPPGHTMEVSC
Tissue specificity：Highly expressed in brain, heart, skeletal muscle and salivary gland, and moderately in kidney and liver. Expressed in dendritic cells, but not in other blood cells. Expression levels are low in pancreatic and liver cancer tissues; absent in meningioma. Expressed in low-grade gliomas but present at low levels in glioblastoma. Isoform 1 and isoform 2 are present in brain neurons and up-regulated in Alzheimer disease (at protein level). {ECO:0000269|PubMed:11352569, ECO:0000269|PubMed:11936845, ECO:0000269|PubMed:12845671, ECO:0000269|PubMed:14572661, ECO:0000269|PubMed:15207261, ECO:0000269|PubMed:15526377, ECO:0000269|PubMed:16103061}.
Induction：
Developmental stage：Specifically expressed during dendritic cell differentiation (in vitro). Expression is low in fetal brain and increases during brain postnatal development. {ECO:0000269|PubMed:14572661, ECO:0000269|PubMed:15207261}.
Protein families：NDRG family