NOG2_HUMAN Q13823
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UniProt:Q13823
Recommended name:Nucleolar GTP-binding protein 2
EC number:
Alternative names:(Autoantigen NGP-1)
Cleaved into:
GeneID:29889
Gene names (primary ):GNL2
Gene names (synonym ):NGP1
Gene names (ORF ):
Length:731
Mass:83655
Sequence:MVKPKYKGRSTINPSKASTNPDRVQGAGGQNMRDRATIRRLNMYRQKERRNSRGKIIKPLQYQSTVASGTVARVEPNIKWFGNTRVIKQSSLQKFQEEMDTVMKDPYKVVMKQSKLPMSLLHDRIRPHNLKVHILDTESFETTFGPKSQRKRPNLFASDMQSLIENAEMSTESYDQGKDRDLVTEDTGVRNEAQEEIYKKGQSKRIWGELYKVIDSSDVVVQVLDARDPMGTRSPHIETYLKKEKPWKHLIFVLNKCDLVPTWATKRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQFGKLHTDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVYPSEDSETDIVLKGVVQVEKIKSPEDHIGAVLERAKPEYISKTYKIDSWENAEDFLEKLAFRTGKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEPLVAPQLLPSSSLEVVPEAAQNNPGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKINVVPQFSGDDLVPVEVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFRQKQ
Tissue specificity:Widely expressed, with the highest expression level in testis. {ECO:0000269|PubMed:8822211}.
Induction:
Developmental stage:Up-regulated in actively dividing cells, including in peripheral blood mononuclear cells stimulated with Concanavalin-A. Down-regulated in differentiating cells, including in neural precursor cells induced to differentiate into astrocytes. {ECO:0000269|PubMed:21495629}.
Protein families:TRAFAC class YlqF/YawG GTPase family, NOG2 subfamily