UCHL1_MOUSE   Q9R0P9


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UniProt:Q9R0P9

Recommended name:Ubiquitin carboxyl-terminal hydrolase isozyme L1

EC number:EC 3.4.19.12

Alternative names:(UCH-L1) (Neuron cytoplasmic protein 9.5) (PGP 9.5) (PGP9.5) (Ubiquitin thioesterase L1)

Cleaved into:

GeneID:22223

Gene names  (primary ):Uchl1

Gene names  (synonym ):

Gene names  (ORF ):

Length:223

Mass:24838

Sequence:MQLKPMEINPEMLNKVLAKLGVAGQWRFADVLGLEEETLGSVPSPACALLLLFPLTAQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVLKQFLSETEKLSPEDRAKCFEKNEAIQAAHDSVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGASSEDSLLQDAAKVCREFTEREQGEVRFSAVALCKAA

Tissue specificity:Expressed in brain, where it is found in neurons but not in oligodendrocytes or astrocytes. Found in the ganglion cell layer and the inner nuclear layer of the retina (at protein level). Expressed in brain and testis. In the brain, expression is at its lowest in replaceable neurons of hippocampus and olfactory bulb. Highly expressed in senescent pituitary. {ECO:0000269|PubMed:10471497, ECO:0000269|PubMed:12559414, ECO:0000269|PubMed:12913066, ECO:0000269|PubMed:14695319, ECO:0000269|PubMed:15911766}.

Induction:

Developmental stage:

Protein families:Peptidase C12 family


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