UCHL1_MOUSE Q9R0P9
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UniProt:Q9R0P9
Recommended name:Ubiquitin carboxyl-terminal hydrolase isozyme L1
EC number:EC 3.4.19.12
Alternative names:(UCH-L1) (Neuron cytoplasmic protein 9.5) (PGP 9.5) (PGP9.5) (Ubiquitin thioesterase L1)
Cleaved into:
GeneID:22223
Gene names (primary ):Uchl1
Gene names (synonym ):
Gene names (ORF ):
Length:223
Mass:24838
Sequence:MQLKPMEINPEMLNKVLAKLGVAGQWRFADVLGLEEETLGSVPSPACALLLLFPLTAQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVLKQFLSETEKLSPEDRAKCFEKNEAIQAAHDSVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGASSEDSLLQDAAKVCREFTEREQGEVRFSAVALCKAA
Tissue specificity:Expressed in brain, where it is found in neurons but not in oligodendrocytes or astrocytes. Found in the ganglion cell layer and the inner nuclear layer of the retina (at protein level). Expressed in brain and testis. In the brain, expression is at its lowest in replaceable neurons of hippocampus and olfactory bulb. Highly expressed in senescent pituitary. {ECO:0000269|PubMed:10471497, ECO:0000269|PubMed:12559414, ECO:0000269|PubMed:12913066, ECO:0000269|PubMed:14695319, ECO:0000269|PubMed:15911766}.
Induction:
Developmental stage:
Protein families:Peptidase C12 family