TDT_MOUSE P09838
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UniProt:P09838
Recommended name：DNA nucleotidylexotransferase
EC number：EC 2.7.7.31
Alternative names：(Terminal addition enzyme) (Terminal deoxynucleotidyltransferase) (TDT) (Terminal transferase)
Cleaved into：
GeneID：21673
Gene names (primary )：Dntt
Gene names (synonym )：Tdt
Gene names (ORF )：
Length：510
Mass：58266
Sequence：MDPLQAVHLGPRKKRPRQLGTPVASTPYDIRFRDLVLFILEKKMGTTRRAFLMELARRKGFRVENELSDSVTHIVAENNSGSDVLEWLQLQNIKASSELELLDISWLIECMGAGKPVEMMGRHQLVVNRNSSPSPVPGSQNVPAPAVKKISQYACQRRTTLNNYNQLFTDALDILAENDELRENEGSCLAFMRASSVLKSLPFPITSMKDTEGIPCLGDKVKSIIEGIIEDGESSEAKAVLNDERYKSFKLFTSVFGVGLKTAEKWFRMGFRTLSKIQSDKSLRFTQMQKAGFLYYEDLVSCVNRPEAEAVSMLVKEAVVTFLPDALVTMTGGFRRGKMTGHDVDFLITSPEATEDEEQQLLHKVTDFWKQQGLLLYCDILESTFEKFKQPSRKVDALDHFQKCFLILKLDHGRVHSEKSGQQEGKGWKAIRVDLVMCPYDRRAFALLGWTGSRQFERDLRRYATHERKMMLDNHALYDRTKRVFLEAESEEEIFAHLGLDYIEPWERNA
Tissue specificity：Isoform TDT-L: Expressed in the thymus, and, at lower levels, in the bone marrow (PubMed:8464703, PubMed:11136823, PubMed:7556063). Detected in both cycling and noncycling pro-B and pre-B cells (at protein level) (PubMed:11938351). Isoform TDT-S: Expressed in both cycling and noncycling pro-B, but not pre-B, cells (at protein level) (PubMed:11938351). Not detected in mature peripheral or germinal center B cells (PubMed:11938351). {ECO:0000269|PubMed:11136823, ECO:0000269|PubMed:11938351, ECO:0000269|PubMed:7556063, ECO:0000269|PubMed:8464703}.
Induction：
Developmental stage：
Protein families：DNA polymerase type-X family