S18B1_MOUSE D3Z5L6
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UniProt:D3Z5L6
Recommended name：MFS-type transporter SLC18B1
EC number：
Alternative names：(Solute carrier family 18 member B1)
Cleaved into：
GeneID：
Gene names (primary )：Slc18b1
Gene names (synonym )：
Gene names (ORF )：
Length：459
Mass：49009
Sequence：MDEAGSPAPAGTGGGDDPGGSTRETSRRLSREQIFVLVSAASMNLGCMMTYSILGPFFPKEAEKKGASNTMIGMIFGCYALFELLASLVFGKYLVHIGAKFMFIAGMFVSGGVTILFGVLDQLPEGPIFIAMCFLVRIVDAIGFGAAITASSSILAKAFPNNVATVMGSLEVFSGLGLVAGPPLGGLLYQSFGYEVPFIFLGCIVLLMIPLNLYILPSYAQESDPGKQSFWKLVTLPKMGLLAFVIISLSSCFGFLDPTLSLFVMEKFSLSTGYVGLVFLGLSLSYAISSPLFGLLSDKMPTLRKWLLVFGNLITAGCYMLLGPVPLLHIKSQLWLLVLVLVVNGISAGMSIIPTFPEMLSCAYANGFEDSISTLGLVSGLFGAMWSVGAFMGPILGGFLCEKIGFEWAAAMQGLWTLLSGVSMALFYLWEDSTARRRSKAQNSLGTEEERAALLPNDT
Tissue specificity：Widely expressed, with highest expression in the lung, pancreas and kidney. High expression in the CNS, particularly in the hypothalamus, the thalamus and the cerebellum. In the forebrain, abundantly expressed in the telencephalon, especially in the cerebral cortex layers, except layer 1, as well as in the induseum griseum, the piriform area, the taenia tecta, dorsal part and in the entorhinal area, lateral part. Lower levels in the bed anterior olfactory nucleus, posteroventral part and in layer two of the olfactory tubercle. In the amygdala, high levels observed in the intercalated nucleus and the medial nucleus. In the diencephalon, expressed in the nuclei in both the hypothalamus and thalamus. Among the hypothalamic areas, strongest expression in the arcuate nucleus and in the ventromedial nucleus, as well as in the suprachiasmatic nucleus, anterior nucleus, especially in its central part, and in the magnocellular division of the paraventricular nucleus. In the thalamus, highest levels in the medial habenula. Expression also observed in the paraventricular thalamic nucleus, parataenial nucleus, central medial nucleus, intermediodorsal nucleus and lateral dorsal nucleus. In the hindbrain, detected in the cerebellum and in the pons. In the midbrain and the medulla, expression levels were modest. In the midbrain, highest expression in the periaqueductal gray and all subdivisions of the interpeduncular nucleus, except for the caudal part. In the pons, the strongest labeling was seen in the nucleus incertus and in the tegmental nucleus. {ECO:0000269|PubMed:19697161}.
Induction：
Developmental stage：
Protein families：Major facilitator superfamily