UT2_MOUSE Q8R4T9
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UniProt:Q8R4T9
Recommended name：Urea transporter 2
EC number：
Alternative names：(Solute carrier family 14 member 2) (Urea transporter, kidney)
Cleaved into：
GeneID：27411
Gene names (primary )：Slc14a2
Gene names (synonym )：Ut2
Gene names (ORF )：
Length：930
Mass：102047
Sequence：MSDHHPLKEMSDSNSSPLLPEPLSSRYKLYESELSSPTWPSSSQDTHPALPLLEMPEEKDLRSSDEDSHIVKIEKPNERNKRRESEVSRRASAGRGGFSLFQAVSYLTGDMKECKNWLKDKPLVLQFLDWVLRGAAQVMFVNNPISGLIIFIGLLIQNPWWTIAGTLGTVASTLAALALSQDRSAIASGLHGYNGMLVGLLMAVFSEKLDYYWWLLFPVTFTSMACPIISSALSTIFAKWDLPVFTLPFNIALTLYLAATGHYNLFFPTTLIKPASAAPNITWTEIEMPLLLQTIPVGVGQVYGCDNPWTGGVILVALFISSPLICLHAAIGSIVGLLAALTVATPFETIYLGLWSYNCVLSCIAIGGMFYALTWQTHLLALVCALFCAYMGAALSNTMAVVGVPSGTWAFCLSTLTFLLLTSNNTGIYKLPLSKVTYPEANRIYFLTVRRSEEEKSPNGGSGEQSHGSGQWKAEESSETVLPRRRSVFHIEWSSIRRRSKVFGKGEHQERQTKEPLPCPYRKPTVELFDLDTMEESTEIKVEANTARTSWIQSSMVAGGKRVSKALSYITGEMKECGEGLKDKSPVFQFLDWVLRGMSQVMFVNNPLSGILIVLGLFVQNPWWAISGCLGTVMSTLTALILSQDKSAIAAGLHGYNGVLVGLLMAVFSDKGNYYWWLLLPVIVMSMTCPILSSALSTVFSKWDLPVFTLPFNIAVTLYLAATGHHNLFFPTTLLQPATTTPNITWSDIQVSLLLRAIPVGIGQVYGCDNPWTGGIFLVALFISSPLICLHAAIGSTIGMLAALSIATPFDSIYFGLCGFNSTLACIAIGGMFYVITWQTHLLAIACALFAAYLGAALANMLSVFGLPPCTWPFCLSALTFLLLTSNNPAIYKLPLSKVTYPEANRIYFLSQEKNRRASTITKYQAYDVS
Tissue specificity：Highly expressed in kidney medulla. Also detected at the protein level in testes, heart, brain and liver. In the kidney, present in thin descending limbs of the loop of Henle and in the middle and terminal inner medullary collecting ducts. Isoform A5 is expressed in the peritubular myoid cells forming the outermost layer of the seminiferous tubules within the testes and is not detected in kidney. Isoform A5 mRNA levels are coordinated with the stage of testes development and increase 15 days postpartum, commensurate with the start of seminiferous tubule fluid movement. {ECO:0000269|PubMed:12217874}.
Induction：
Developmental stage：
Protein families：Urea transporter family