PPM1K_MOUSE Q8BXN7
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UniProt:Q8BXN7
Recommended name:Protein phosphatase 1K, mitochondrial
EC number:EC 3.1.3.16
Alternative names:(Protein phosphatase 2C isoform kappa) (PP2C-kappa)
Cleaved into:
GeneID:243382
Gene names (primary ):Ppm1k
Gene names (synonym ):Pp2cm
Gene names (ORF ):
Length:372
Mass:40918
Sequence:MLSAAFITLLRSGGNQVKKRVLLSSILLQDHRQATPACYFSTSEARCSRFDPDGSGQPATWDNFGIWDNRIDEPILLPPSIKYGKPIPKISLENVGCASLIGKRKENEDRFGFAQLTEEVLYFAVYDGHGGPAAADFCHTHMEKCVMDLLPREKDLETVLTLAFLEIDKAFASYAHLSADASLLTSGTTATVALLRDGVELVVASVGDSRALLCRKGKPMKLTTDHTPERKDEKERIKKFGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKASGVIAEPETTRIKLYHADDSFLVLTTDGINFMVNSQEICDFVNQCHDPKEAAHSVTEQAIQYGTEDNSTAVVVPFGAWGKYKNSEITFSFSRSFASSGRWA
Tissue specificity:Highly expressed in the heart, kidney, brain and liver and to a lesser extent in testis, lung, spleen and adipose tissue. Very low amount in muscle (at protein level). Also expressed in the thymus (at protein level) and the diaphragm. Significantly reduced in hypertrophied hearts. {ECO:0000269|PubMed:17336929, ECO:0000269|PubMed:17374715}.
Induction:
Developmental stage:
Protein families:PP2C family