PDCD4_MOUSE Q61823
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UniProt:Q61823
Recommended name:Programmed cell death protein 4
EC number:
Alternative names:(Protein MA-3) (Topoisomerase-inhibitor suppressed protein)
Cleaved into:
GeneID:18569
Gene names (primary ):Pdcd4
Gene names (synonym ):Ma3 Tis
Gene names (ORF ):
Length:469
Mass:51702
Sequence:MDIENEQTLNVNPTDPDNLSDSLFSGDEENAGTEEIKNEINGNWISASTINEARINAKAKRRLRKNSSRDSGRGDSVSDNGSEAVRSGVAVPTSPKGRLLDRRSRSGKGRGLPKKGGAGGKGVWGTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLPLDETAFEKTLTPIIQEYFEHGDTNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTNDVEKSFDKLLKDLPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATVLLSMSKGGKRKDSVWGSGGGQQPVNHLVKEIDMLLKEYLLSGDISEAEHCLKELEVPHFHHELVYEAIVMVLESTGESAFKMILDLLKSLWKSSTITIDQMKRGYERIYNEIPDINLDVPHSYSVLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY
Tissue specificity:Expressed ubiquitously. Highyly expressed in thymus and liver. Moderately expressed in brain, kidney and spleen; weakly in lung and heart. Expression is up- or down-regulated in response to apoptosis inducers. Regulated by many programmed cell death-inducing stimuli. {ECO:0000269|PubMed:8543179, ECO:0000269|PubMed:9714845}.
Induction:
Developmental stage:
Protein families:PDCD4 family