PPCEL_MOUSE Q8C167
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UniProt:Q8C167
Recommended name:Prolyl endopeptidase-like
EC number:EC 3.4.21.-
Alternative names:(Prolylendopeptidase-like)
Cleaved into:
GeneID:213760
Gene names (primary ):Prepl
Gene names (synonym ):Kiaa0436
Gene names (ORF ):
Length:725
Mass:83194
Sequence:MLQTAKFSLRALKHSIPHLGNCMQKQSYRNVAGPYYSRVRLKKYHLTKCLQNKPRIAGLARNIPSRSFSCKDLLPIKPESEKPISENMDAFEKVRTRLETQPQEEYEVVNAEIKHGGFVYYQEGCCLVRSKDEEADSDNYEVLFNLEELKLDQPFIDCIRVAPDEKYVAAKIRTEDSETSTLVVVKLSDQPVMEASFPNVSSFEWVKDEEDEDVLFYTFQRNLRCHDVYRATFGDNKRNERFYTEKDPSYFVFLYLTKDSRFLTLNIMNKTTSEVWLIDGLSPWDPPVLIQKRIHGMLYYVEHRDDELYILTNVGEPTEFKLMRTAADAPAIMNWDLFFTMKRNTKVVDLDMFKDHCVLFLKHSNLLYVNVIGLADDSVRSLKLPPWACGFIMDTNSDPKNCPFQLCSPIRPPKYYTYKFAEGKLFEETGHEDPITKTSRVLRIEAKSKDGKLVPMTVFHKTDSEDLQRKPLLVHVYGAYGMDLKMNFRPEKRVLVDDGWILAYCHVRGGGELGLQWHADGRLTKKLNGLADLVACIKTLHSQGFSQPSLTTLSAFSAGGVLVGALCNSKPELLRAVTLEAPFLDVLNTMLDTTLPLTLEELEEWGNPSSDEKHKNYIKRYCPCQNIKPQHYPSVHITAYENDERVPLKGIVNYTEKLKEAVAEHTKGAGEGYQPPNIILDIQPGGNHVIEDSHKKITTQMKFLYEELGLDSTDAFEALKKYLKF
Tissue specificity:Highly expressed in the brain, specifically in neurons of the neocortex, substantia nigra, locus coeruleus, and cerebellum, and a slightly lesser extent in neurons in the hypothalamus and hippocampus (at protein level) (PubMed:23321636, PubMed:23485813). Also expressed in interneurons in the stratum lacunosum moleculare and stratum radiatum (PubMed:23485813). {ECO:0000269|PubMed:23321636, ECO:0000269|PubMed:23485813}.
Induction:
Developmental stage:
Protein families:Peptidase S9A family