PPCEL_MOUSE   Q8C167


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UniProt:Q8C167

Recommended name:Prolyl endopeptidase-like

EC number:EC 3.4.21.-

Alternative names:(Prolylendopeptidase-like)

Cleaved into:

GeneID:213760

Gene names  (primary ):Prepl

Gene names  (synonym ):Kiaa0436

Gene names  (ORF ):

Length:725

Mass:83194

Sequence:MLQTAKFSLRALKHSIPHLGNCMQKQSYRNVAGPYYSRVRLKKYHLTKCLQNKPRIAGLARNIPSRSFSCKDLLPIKPESEKPISENMDAFEKVRTRLETQPQEEYEVVNAEIKHGGFVYYQEGCCLVRSKDEEADSDNYEVLFNLEELKLDQPFIDCIRVAPDEKYVAAKIRTEDSETSTLVVVKLSDQPVMEASFPNVSSFEWVKDEEDEDVLFYTFQRNLRCHDVYRATFGDNKRNERFYTEKDPSYFVFLYLTKDSRFLTLNIMNKTTSEVWLIDGLSPWDPPVLIQKRIHGMLYYVEHRDDELYILTNVGEPTEFKLMRTAADAPAIMNWDLFFTMKRNTKVVDLDMFKDHCVLFLKHSNLLYVNVIGLADDSVRSLKLPPWACGFIMDTNSDPKNCPFQLCSPIRPPKYYTYKFAEGKLFEETGHEDPITKTSRVLRIEAKSKDGKLVPMTVFHKTDSEDLQRKPLLVHVYGAYGMDLKMNFRPEKRVLVDDGWILAYCHVRGGGELGLQWHADGRLTKKLNGLADLVACIKTLHSQGFSQPSLTTLSAFSAGGVLVGALCNSKPELLRAVTLEAPFLDVLNTMLDTTLPLTLEELEEWGNPSSDEKHKNYIKRYCPCQNIKPQHYPSVHITAYENDERVPLKGIVNYTEKLKEAVAEHTKGAGEGYQPPNIILDIQPGGNHVIEDSHKKITTQMKFLYEELGLDSTDAFEALKKYLKF

Tissue specificity:Highly expressed in the brain, specifically in neurons of the neocortex, substantia nigra, locus coeruleus, and cerebellum, and a slightly lesser extent in neurons in the hypothalamus and hippocampus (at protein level) (PubMed:23321636, PubMed:23485813). Also expressed in interneurons in the stratum lacunosum moleculare and stratum radiatum (PubMed:23485813). {ECO:0000269|PubMed:23321636, ECO:0000269|PubMed:23485813}.

Induction:

Developmental stage:

Protein families:Peptidase S9A family


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