ENDOU_MOUSE   Q3V188


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UniProt:Q3V188

Recommended name:Poly(U)-specific endoribonuclease

EC number:EC 3.1.-.-

Alternative names:(Placental protein 11-related protein) (PP11-related protein) (Protein endoU) (T-cell-specific protein 30) (Tcl-30) (Uridylate-specific endoribonuclease)

Cleaved into:

GeneID:19011

Gene names  (primary ):Endou

Gene names  (synonym ):Pp11r

Gene names  (ORF ):

Length:412

Mass:47010

Sequence:MKARVPFIVAMLCGLAWAGNLESCASRCHEKFNRDAVCQCDRRCPQHDDCCDDYEHLCTAEEGPPEPEAFLDPEDKIPTSHLYSAPSSCQGRCREAYDKHHPCHCNDRCPEFGNCCEDFDSLCGGDHEGFSHSSDAVTKEELESISETIYRVDTNKAQKEDIVLNSQNRISPSETGNQVDRSPEPLFTYVNEKLFSKPTYAAFINLLNNYQRATGHGEHFSAQQLEEQGVFLREVMKTAVMKELYSFLHHQNRYSSEQEFVDDLKNMWFGLYSRGNDEGDSSGFEHVFSGEVKKGKVTGFHNWIRFYLQEKEGLLDYYSHNYDGPWDSYPDVLAMQFNWDGYYKEVGSVFIGSSPEFEFALYSLCFITRPGKKCHLSLGGYPLAIQTYTWDKTTYGNGKKYIATAYVVSSSQ

Tissue specificity:Specifically expressed in T-cells during apoptosis. Expressed in surface heat stable antigen (HSA)-containing T-cells populations (CD4(-)CD8(-)HSA(+), CD4(+)CD8(-)HSA(+), CD4(-)CD8(+)HSA(+), and CD4(+)CD8(+)HSA(+)) and not in the HSA(-) single positive T-cell populations of the thymus or spleen, suggesting that expression is lost during T-cell maturation and is absent at the most mature stages of T-cell development. {ECO:0000269|PubMed:1506680, ECO:0000269|PubMed:8104059}.

Induction:

Developmental stage:

Protein families:ENDOU family


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