NEUS_MOUSE O35684
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UniProt:O35684
Recommended name:Neuroserpin
EC number:
Alternative names:(Peptidase inhibitor 12) (PI-12) (Serine protease inhibitor 17) (Serpin I1)
Cleaved into:
GeneID:20713
Gene names (primary ):Serpini1
Gene names (synonym ):Pi12 Spi17
Gene names (ORF ):
Length:410
Mass:46348
Sequence:MTYLELLALLALQSVVTGATFPDETITEWSVNMYNHLRGTGEDENILFSPLSIALAMGMMELGAQGSTRKEIRHSMGYEGLKGGEEFSFLRDFSNMASAEENQYVMKLANSLFVQNGFHVNEEFLQMLKMYFNAEVNHVDFSQNVAVANSINKWVENYTNSLLKDLVSPEDFDGVTNLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLALSRQEVPLATLEPLLKAQLIEEWANSVKKQKVEVYLPRFTVEQEIDLKDILKALGVTEIFIKDANLTAMSDKKELFLSKAVHKSCIEVNEEGSEAAAASGMIAISRMAVLYPQVIVDHPFLYLIRNRKSGIILFMGRVMNPETMNTSGHDFEEL
Tissue specificity:Detected in neurons in embryonic brain cortex (at protein level) (PubMed:17040209). During embryonic development mostly expressed in CNS (PubMed:9364046). In adult expressed in brain and much less in spinal cord, heart, kidney and testis (PubMed:9364046). {ECO:0000269|PubMed:17040209, ECO:0000269|PubMed:9364046}.
Induction:
Developmental stage:
Protein families:Serpin family