PDGFD_MOUSE Q925I7
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UniProt:Q925I7
Recommended name：Platelet-derived growth factor D
EC number：
Alternative names：(PDGF-D) (Spinal cord-derived growth factor B) (SCDGF-B)
Cleaved into：Platelet-derived growth factor D, latent form (PDGFD latent form); Platelet-derived growth factor D, receptor-binding form (PDGFD receptor-binding form)
GeneID：71785
Gene names (primary )：Pdgfd
Gene names (synonym )：Scdgfb
Gene names (ORF )：
Length：370
Mass：42809
Sequence：MQRLVLVSILLCANFSCYPDTFATPQRASIKALRNANLRRDESNHLTDLYQREENIQVTSNGHVQSPRFPNSYPRNLLLTWWLRSQEKTRIQLSFDHQFGLEEAENDICRYDFVEVEEVSESSTVVRGRWCGHKEIPPRITSRTNQIKITFKSDDYFVAKPGFKIYYSFVEDFQPEAASETNWESVTSSFSGVSYHSPSITDPTLTADALDKTVAEFDTVEDLLKHFNPVSWQDDLENLYLDTPHYRGRSYHDRKSKVDLDRLNDDVKRYSCTPRNHSVNLREELKLTNAVFFPRCLLVQRCGGNCGCGTVNWKSCTCSSGKTVKKYHEVLKFEPGHFKRRGKAKNMALVDIQLDHHERCDCICSSRPPR
Tissue specificity：Expressed at high levels in developing heart, lung, kidney and some muscle derivatives. Moderately expressed in liver, brain and testis. In the kidney, localized to glomerular mesangial cells and vascular smooth muscle cells. Up-regulated in areas of renal fibrosis. In mice with unilateral ureteral obstruction, expressed in interstitial cells at day 4, with an increased to maximal expression at day 14. {ECO:0000269|PubMed:11331881, ECO:0000269|PubMed:12890490, ECO:0000269|PubMed:14514732, ECO:0000269|PubMed:14747375}.
Induction：
Developmental stage：
Protein families：PDGF/VEGF growth factor family