PDGFB_MOUSE P31240
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UniProt:P31240
Recommended name：Platelet-derived growth factor subunit B
EC number：
Alternative names：(PDGF subunit B) (PDGF-2) (Platelet-derived growth factor B chain) (Platelet-derived growth factor beta polypeptide) (Proto-oncogene c-Sis)
Cleaved into：
GeneID：18591
Gene names (primary )：Pdgfb
Gene names (synonym )：Sis
Gene names (ORF )：
Length：241
Mass：27382
Sequence：MNRCWALFLPLCCYLRLVSAEGDPIPEELYEMLSDHSIRSFDDLQRLLHRDSVDEDGAELDLNMTRAHSGVELESSSRGRRSLGSLAAAEPAVIAECKTRTEVFQISRNLIDRTNANFLVWPPCVEVQRCSGCCNNRNVQCRASQVQMRPVQVRKIEIVRKKPIFKKATVTLEDHLACKCETIVTPRPVTRSPGTSREQRAKTPQARVTIRTVRIRRPPKGKHRKFKHTHDKAALKETLGA
Tissue specificity：Localized to vascular smooth muscle cells. Also weakly expressed by cortical interstitial cells but absent in tubules. Up-regulated in areas of renal fibrosis. In mice with unilateral ureteral obstruction, an increased expression in interstitial cells and in some tubules observed after day 4. {ECO:0000269|PubMed:14514732}.
Induction：
Developmental stage：
Protein families：PDGF/VEGF growth factor family