UBR3_MOUSE Q5U430
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UniProt:Q5U430
Recommended name：E3 ubiquitin-protein ligase UBR3
EC number：EC 2.3.2.27
Alternative names：(N-recognin-3) (RING-type E3 ubiquitin transferase UBR3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650)
Cleaved into：
GeneID：68795
Gene names (primary )：Ubr3
Gene names (synonym )：Kiaa2024 Zfp650 Znf650
Gene names (ORF )：
Length：1889
Mass：212757
Sequence：MAAAAAAAAVGDPQPPQPEAPAQGLALDKAATAAHLKAALSRPDNRAGAEELQALLERVLNAERPLAGAAGGEEAAGGGGGGPGEAEEDALEWCKCLLAGGGGYEEFCAAVRAYDPAALCGLVWTANFVAYRCRTCGISPCMSLCAECFHQGDHTGHDFNMFRSQAGGACDCGDSNVMRESGFCRRHQIKSSSNIPCVPKDLLMMSEFVLPRFIFCLIQYLREGYNEPAADAPSEKDLNKVLQLLEPQISFLEDLTKMGGAMRSVLTQVLTNQQNYKDLTAGLGENACAKKSHEKYLIALKSSGLTYPEDKLVYGVQEPAAGTSTLAAQGFAGATGTLGQIDSSDEEDQDGSQGLGKRKRVKLSSGTKDQSIMDVLKHKSFLEELLFWTIKYEFPQKMVTFLLNMLPDQEYKVAFTKTFVQHYAFIMKTLKKSHESDTMSNRIVHISVQLFSNEELARQVTEECQLLDIMVTVLLYMMESCLIKSELQDEENSLHVVVNCGEALLKNNTYWPLVSDFINILSHQSVAQRFLEDHGLLVTWMNFVSFFQGMNLNKRELNEHVEFESQTYYAAFAAELEACAQPMWGLLSHCKVRETQEYTRNVVRYCLEALQDWFDAINFVDEPAPNQVTFHLPLHRYYAMFLSKAVKCQELDLDSLLPDQEMLMKLMIHPLQIQASLAEIHSNMWVRNGLQIKGQAMTYVQSHFCNSMIDPDIYLLQVCASRLDPDYFISSVFERFKVVDLLTMASQHHNMVLDVEHERSMLEGALTFLVILLSLRLHLGMSDDDILRAEMVAQLCMNDRTHSSLLDLIPENPNPKSGIIPGSYSFESVLSAVADFRAPIFEPGGSMQQGMYTPKAEVWDQEFDPVMVILRTVYRRDVQSAMDRYTAFLKQSGKFPGNPWPPYKKRTSLHPSYKGLMRLLHCKTLHIVLFTLLYKILMDHQNLSEHVLCMVLYLIELGLENSADDDSEEEVSMGGPERCHDSWFPGSNLVSNMRHFINYVRVRVPETAPELKRDPLASTSSDALDSLQNSGTAQVFSLVAERRKKFQEIINRSNSEANQVVRPKIPSKWSAPGSSPQLTTAILEIKESILSLLIKLHHKLSGKQNSYYPPWLDDIEVLIQPEIPKYNHGDGITAVERILLKAAVQSRMNKRIIEEICRKVTPPVPPKKITAAEKKTLDKEERRQKARERQQKLLAEFASRQKSFMETAMDVDSPENDIPMEITTAEPQVSEAVYDCVICGQSGPSSEDRPTGLVVLLQASSVLGQCRDNAEPKKLPIAEEEQIYPWDTCAAVHDVRLSLLQRYFKDSSCLLAVSIGWEGGVYVQTCGHTLHIDCHKSYMESLRNDQVLQGFSVDKGEFTCPLCRQFANSVLPCYPGSNVENNLWQRPCNKSTQDLIKEVEELQGRPGAFPSETNLSKEMESVMKDIKNTTQKKYRDYSKTPGSPDNEFLFMYSVARTNLELELIHRGGSLCSGGPSTAGKRSCLNQLFHVLALHMRLYTIDSEYNPWKKLTQLVEDMNSQVGNEDQQPEVPILYHDVTSLLLIQILMMPQPLRKEHFTCIVKVLFTLLYTQALAALSVKGTEEDRSAWKHAGALRKDTCDAEKCYEVLLSFVISELSKGKLYYEEGAQECAMVSPIAWSPESMERYIQDFCLPFLRVSSLLQHHLFGEDLPSCQEEEEFSVLASCLGLLPTFYQTDHPFISASCLDWPVAAFDIITQWCFEITSFTERHAEQGKALLIQESRWKLPHLLQLPENYNTIFQYYHRKTCSVCTKVPKDPAVCLVCGTFVCLKGLCCKQQSYCECVLHSQNCGAGTGIFLLINASVIIIIRGHRFCLWGSVYLDAHGEEDRDLRRGKPLYICEERYRVLEQQWVSHTFDHINKRWGPHYNGL
Tissue specificity：Expressed in numerous cells of the smell, touch, vision, hearing and taste senses. Expressed in cells of the olfactory pathway, including the olfactory cell layer of the main olfactory epithelium (MOE), a mitral neuron cell layer of the olfactory bulb (OB), and a pyramidal cell layer of the piriform cortex of the olfactory cortex (OC). Expressed in the vomeronasal sensory epithelium of the vomeronasal organ (VNO) and the mitral cells of the accessory olfactory bulb. Expressed in tactile tissues, including the dorsal root ganglion, trigeminal ganglion and follicle-sinus complexes. Expressed in cells between hair follicle and sinus and also in the region of the rete ridge collar. Expressed in taste buds of the fungiform, circumvallate, and foliate papillae. Expressed in the spiral ganglion, the organ of Corti of the cochlea in the inner ear, in the sensory epithelium of macula and vestibular ganglion of the balancing system (at protein level). Expressed in the liver and skeletal muscle. {ECO:0000269|PubMed:17462990}.
Induction：
Developmental stage：
Protein families：UBR1 family