GSDME_MOUSE Q9Z2D3
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UniProt:Q9Z2D3
Recommended name：Gasdermin-E
EC number：
Alternative names：(Non-syndromic hearing impairment protein 5 homolog)
Cleaved into：Gasdermin-E, N-terminal (GSDME-NT); Gasdermin-E, C-terminal (GSDME-CT)
GeneID：54722
Gene names (primary )：Gsdme
Gene names (synonym )：Dfna5 Dfna5h
Gene names (ORF )：
Length：512
Mass：56631
Sequence：MFAKATRNFLKEVDAGGDLISVSHLNDSDKLQLLSLVTKKKRYWCWQRPKYQILSATLEDVLTEGHCLSPVVVESDFVKYESKCENHKSGAIGTVVGKVKLNVGGKGVVESHSSFGTLRKQEVDVQQLIQDAVKRTVNMDNLVLQQVLESRNEVLCVLTQKIMTTQKCVISEHVQSEETCGGMVGIQTKTIQVSATEDGTVTTDTNVVLEIPAATTIAYGIMELFVKQDGQFEFCLLQGKHGGFEHERKLDSVYLDPLAYREFAFLDMLDGGQGISSQDGPLRVVKQATLHLERSFHPFAVLPAQQQRALFCVLQKILFDEELLRALEQVCDDVAGGLWSSQAVLAMEELTDSQQQDLTAFLQLVGYRIQGEHPGPQDEVSNQKLFATAYFLVSALAEMPDNATVFLGTCCKLHVISSLCCLLHALSDDSVCDFHNPTLAPLRDTERFGIVQRLFASADIALERMQFSAKATILKDSCIFPLILHITLSGLSTLSKEHEEELCQSGHATGQD
Tissue specificity：Expressed in spleen, kidney, large and small intestine, testicle, stomach and by CD4(+)CD(8+) T cells in thymus (PubMed:28459430). Expressed by macrophages (PubMed:28045099). {ECO:0000269|PubMed:28045099, ECO:0000269|PubMed:28459430}.
Induction：
Developmental stage：
Protein families：Gasdermin family