ASAH2_MOUSE Q9JHE3
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UniProt:Q9JHE3
Recommended name：Neutral ceramidase
EC number：EC 3.5.1.-
Alternative names：(N-CDase) (NCDase) (Acylsphingosine deacylase 2) (N-acylsphingosine amidohydrolase 2)
Cleaved into：Neutral ceramidase soluble form
GeneID：54447
Gene names (primary )：Asah2
Gene names (synonym )：
Gene names (ORF )：
Length：756
Mass：83509
Sequence：MAKRTFSTLEAFLIFLLVIMTVITVALLTLLFVTSGTIENHKDSGNHWFSTTLGSTTTQPPPITQTPNFPSFRNFSGYYIGVGRADCTGQVSDINLMGYGKNGQNARGLLTRLFSRAFILADPDGSNRMAFVSVELCMISQRLRLEVLKRLESKYGSLYRRDNVILSAIHTHSGPAGFFQYTLYILASEGFSNRTFQYIVSGIMKSIDIAHTNLKPGKIFINKGNVANVQINRSPSSYLLNPQSERARYSSNTDKEMLVLKLVDLNGEDLGLISWFAIHPVSMNNSNHFVNSDNMGYAAYLFEQEKNKGYLPGQGPFVAGFASSNLGDVSPNILGPHCVNTGESCDNDKSTCPNGGPSMCMASGPGQDMFESTHIIGRIIYQKAKELYASASQEVTGPVLAAHQWVNMTDVSVQLNATHTVKTCKPALGYSFAAGTIDGVSGLNITQGTTEGDPFWDTLRDQLLGKPSEEIVECQKPKPILLHSGELTIPHPWQPDIVDVQIVTVGSLAIAAIPGELTTMSGRRFREAIKKEFALYGMKDMTVVIAGLSNVYTHYITTYEEYQAQRYEAASTIYGPHTLSAYIQLFRDLAKAIATDTVANMSSGPEPPFFKNLIASLIPNIADRAPIGKHFGDVLQPAKPEYRVGEVVEVIFVGANPKNSAENQTHQTFLTVEKYEDSVADWQIMYNDASWETRFYWHKGILGLSNATIYWHIPDTAYPGIYRIRYFGHNRKQELLKPAVILAFEGISSPFEVVTT
Tissue specificity：Widely expressed (PubMed:10753931, PubMed:14557071). Strongly expressed in small intestine and to a lower extent in liver and kidney (PubMed:10753931). Highly expressed in duodenum, jejunum and ileum along the brush border of the small intestine (at protein level) (PubMed:16380386). {ECO:0000269|PubMed:10753931, ECO:0000269|PubMed:14557071, ECO:0000269|PubMed:16380386}.
Induction：
Developmental stage：
Protein families：Neutral ceramidase family