NCKX4_MOUSE Q8CGQ8
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UniProt:Q8CGQ8
Recommended name：Sodium/potassium/calcium exchanger 4
EC number：
Alternative names：(Na(+)/K(+)/Ca(2+)-exchange protein 4) (Solute carrier family 24 member 4)
Cleaved into：
GeneID：238384
Gene names (primary )：Slc24a4
Gene names (synonym )：Nckx4
Gene names (ORF )：
Length：622
Mass：68974
Sequence：MALRGLIRQSKVRRRREMLPQQVGFVCAVLALVCCASGLFGSLGHKTASAGKHVLLDTWRNRKLMAPINGTPLAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVPSLEKICEKLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVRLTWWAVCRDSVYYTLSVIVLIAFIYDEEIVWWEGLVLIILYVFYILIMKYNMKMQTFFTTKQKSIANGNPVSNELEDGNDLYDGSYDDPSVPLLGQVKEKPPYGKTPVVMVDEILSSSPPKFTFPEAGLRIMITNKFGPRTRLRMASRIIINERQRLINSANGVNSKPLQNGRHENMENGNVPVENPEDPQQGQEQQPPPQPPPPEPESVETVFLSPFSMPEAKGDKAKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYLMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGIPWGLQTMVINYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGIYVLVLYAVFLCFSIMIEFNVFTFVNLPMCREDD
Tissue specificity：Expressed in late secretory-stage and maturation-stage ameloblasts, with significantly increased expression during the late stages of amelogenesis (at protein level) (PubMed:22677781, PubMed:24621671, PubMed:26247047). Widely expressed in most regions of the brain, including hippocampus, neocortex, thalamus, striatum and olfactory bulb (PubMed:12379639). Expressed in the olfactory sensory neurons (PubMed:22057188). {ECO:0000269|PubMed:22057188, ECO:0000269|PubMed:22677781, ECO:0000269|PubMed:24621671, ECO:0000269|PubMed:26247047}.
Induction：
Developmental stage：
Protein families：Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family, SLC24A subfamily