SL9A8_MOUSE Q8R4D1
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UniProt:Q8R4D1
Recommended name:Sodium/hydrogen exchanger 8
EC number:
Alternative names:(Na(+)/H(+) exchanger 8) (NHE-8) (Solute carrier family 9 member 8)
Cleaved into:
GeneID:77031
Gene names (primary ):Slc9a8
Gene names (synonym ):Nhe8
Gene names (ORF ):
Length:576
Mass:64737
Sequence:MAEEEFSNTTHETFNFTLHTTLGVTTKLVLPTPAKPILPVQTGEQAQQEEQSSGMTIFFSLLVLAICIILVHLLIRYRLHFLPESVAVVSLGILMGAVIKVIEFKKLANWKEEEMFRPNMFFLLLLPPIIFESGYSLHKGNFFQNIGSITLFAVFGTAISAFVVGGGIYFLGQADVISKLNMTDSFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFGESILNDAVSIVLTNTAEGLTRKHMSDVSGWQTFSQALGYFLKMFFGSAALGTLTGLISALVLKHIDLRKTPSLEFGMMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTHHNLSPVTQILMQQTLRTVAFLCETCVFAFLGLSIFSFPHKFEISFVIWCIVLVLFGRAVNIFPLSYLLNFFRDHKITPKMMFIMWFSGLRGAIPYALSLHLGLEPMEKRQLIGTTTIVIVLFTILLLGGSTMPLIRLVDIEDARARRRSKKDVNLSKTEKMGNAIESEHLSELTEEEYEAHYIRQQDLKGFMWLDAKYLNPFFTRRLTQEDLHHGRIQMKSLTNKWYEEVRQGPSGSEDDEQELF
Tissue specificity:Ubiquitously expressed. Expressed in both renal cortex and medulla. In the cortex, present in the majority of cortical tubules. In the medulla, most highly expressed in the proximal tubules (S3) of the outer stripe of the outer medulla. {ECO:0000269|PubMed:12409279}.
Induction:
Developmental stage:
Protein families:Monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family