PIWL4_MOUSE Q8CGT6
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UniProt:Q8CGT6
Recommended name:Piwi-like protein 4
EC number:
Alternative names:(mAgo5)
Cleaved into:
GeneID:
Gene names (primary ):Piwil4
Gene names (synonym ):Miwi2
Gene names (ORF ):
Length:848
Mass:95773
Sequence:MSGRARVRARGITTGHSAREVGRSSRDLMVTSASPGDSEAGGGTSVISQPYELGVSSGDGGRTFMERRGKGRQDFEELGVCTREKLTHVKDCKTGSSGIPVRLVTNLFNLDLPQDWQLYQYHVTYSPDLASRRLRIALLYNHSILSDKAKAFDGASLFLSEKLDQKVTELTSETQRGETIKITLTLTSKLFPNSPVCIQFFNVIFRKILKNLSMYQIGRNFYKPSEPVEIPQYKLSLWPGFAISVSHFESKLLFNADVNYKVLRNETVLDFMTDLCLRTGMSCFTEMCHKQLVGLVVLTRYNNKTYRIDDIDWSVKPTQAFQKRDGSEVTYVDYYKQQYDITLSDLNQPVLVSLLKRKRNDNSEPQMVHLMPELCFLTGLSSQATSDFRLMKAVAEETRLSPVGRQQQLARLVDDIQRNPVARFELETWGLHFGSQLSLTGRVVPSEKILLQDHTCQPAFAADWSKDMRSCKVLSSQPLNRWLIVCCNRAEHLIEAFLSCLRRVGGSMGFNVGYPKIIKVDETPAAFLRAIQVHGDPDVQLVMCILPSNQKNYYDSIKKYLSSDCPVPSQCVLTRTLNKQGTMLSVATKIAMQMTCKLGGELWSVEIPLKSLMVVGIDICRDALNKNVVVVGFVASINSRITRWFSRCVLQRTAADIADCLKVCMTGALNRWYRHNHDLPARIVVYRDGVGNGQLKAVLEYEVPQLLKSVTECGSDARSCRLSVVVVRKRCLLRLFASTDHTVQNPPLGTVVDSEATRPEWYDFYLISQTANRGTVSPTHYNVIYDDNALKPDHMQRLTFKLCHLYYNWQGLISVPAPCQYAHKLTFLVAQSVHKEPSLELANNLFYL
Tissue specificity:Detected in male germ cells beginning around 14.5-15.5 dpc but is absent from female germ cells (PubMed:18922463, PubMed:25038252). From 15.5 dpc and until birth, it is present in male germ cells. Not detected in somatic cells of the embryonic gonad. Expression declines soon after birth, reaching undetectable levels in 4 day-old mice (at protein level). {ECO:0000269|PubMed:18922463, ECO:0000269|PubMed:25038252}.
Induction:
Developmental stage:
Protein families:Argonaute family, Piwi subfamily