KMT2D_MOUSE Q6PDK2
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UniProt:Q6PDK2
Recommended name：Histone-lysine N-methyltransferase 2D
EC number：EC 2.1.1.354
Alternative names：(Lysine N-methyltransferase 2D) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2)
Cleaved into：
GeneID：
Gene names (primary )：Kmt2d
Gene names (synonym )：Mll2 Mll4
Gene names (ORF )：
Length：5588
Mass：600245
Sequence：MDSQKPPAEDKDSDPAADGLAAPEKPGATEPDLPILCIGEVSVPGSGGSRPQKPPHDCSRGPARRCALCNCGEPGLHGQRELQRFELPSDWPGFPVVPSGGNSGPCEAVLPKEDASQIGFPEGLTPAHLGEPGGHCWAHHWCAAWSAGVWGQEGPELCGVDKAIFSGISQRCSHCARFGASVPCRSPGCSRLYHFPCATASGSFLSMKTLQLLCPEHSDGAAHLEEARCAVCEGPGQLCDLLFCTSCGHHYHGACLDTALTARKRASWQCPECKVCQSCRKPGNDSKMLVCETCDKGYHTFCLKPPMEDLPAHSWKCKTCRLCRACGAGSAELNPNSEWFENYSLCHRCHKAQGSQPVTSVAEQHPAVCSRLSPPEPGEIPIDAPDALYVACQGQPKGGHVTSMQPKELAPLQCEAKPLGRAGTQLEAQLEAPLHEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPTEESPLSPPPESSPFSPLEGCPPSPALDTPLSPPPEASPLSPPFEESPLSPPPEELPSSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEDSPLSPPPEASRLSPPPEDSPMSPPPEDSPMSPPPEVSRFLPLPVLSHLSPLPEVSRLSPPPEESPLSPPPEDSPASPPPEASRLSPPPEDSPASPPPEASRLSRPREDSPASPPPEDSLVSLPMEESPLSPLPEELRLCPQPEEPYLSPQPEEPRLCPQPEELPLSPQSEEPCLSPVLVEPGPSSQPEEPHLSPVPQEPHLSPQPEEPHLSPQPQQLHLSPHSEEPCLSPMPEEPCLSPQPEELNGPPQPAEPPEEPSQSSAPKELSLFSPSGEPPLPPMLGEPALSEPGEPPLSPLPEELPLSLSGEPVLSPQLMPPDPLPPPLSPIIPAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPLGPASPILMERLPPPCSPLLPHSLPPPTPPPSHCSPPALPLSVPSPLSPVQKAVDVSDEAELHEMETDKGPEPECPALEPRATSPLPSPLGDLSCPAPSPAPALDDFSGLGEDTAPLDGTGQMSGSLAGELKGSPVLLDPEELTPVTPMEVYGPECKQAGQGSPCEEQEEPGAPMAPMPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARDEGSLRLCTDSLPETDDSLLCDTGTATSGGKAEGDKGRRRSSPARSRIKQGRSSSFPGRRRPRGGAAHGGRGRGRARLKSTTSSVETLVADIDSSPSKEEEEEDDDTMQNTVVLFSNTDKFVLMQDMCVVCGSFGRGAEGHLLACSQCSQCYHPYCVNSKITKVMLLKGWRCVECIVCEVCGQASDPSRLLLCDDCDISYHTYCLDPPLLTVPKGGWKCKWCVSCMQCGAASPGFHCEWQNSYTHCGPCASLVTCPVCHAPYVEEDLLIQCRHCERWMHAGCESLFTEDEVEQAADEGFDCVSCQPYVVKPVVPVAPPELVPVKVKEPEPQFFRFEGVWLTETGMAVLRNLTMSPLHKRRQRRGRLGLPGEAGLEGSEPSDALGPDDKKDGDLDTDDLLKGEGGVEQMECEIKLEGPASPDVELGKEETEESKKRKRKPYRPGIGGFMVRQRKSHTRVKRGPAAQAEVLSGDGQPDEVMPADLPAEGSVEQSLAEGDEKKKQQRRARKKSKLEDMFPAYLQAAFFGKDLLDLSRKALFAVGVGRPGFGLGASKPRADGGSDRKELMTAMHKGDDGPDVADEESHGPEGTADLPGLEDGGVKASPVPSDPEKPGTPGEGVLSSDLDRIPTEELPKMESKDLQQLFKDVLGSEREQHLGCGTPGLEGGRTSLQRPFLQGGLALGSLPSSSPMDSYPGLCQSPFLDSRERGGFFSPEPGEPDSPWTGSGGTTPSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANINFPNLKQDYPDWSSRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRISKVQKQAESQISKQAKMGDIARKTDRPALHLRIPSQPGALGSPPPAAAPTIFLGSPTTPAGLSTSADGFLKPPAGTVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYAPEPRFSAAPPTYPPYPSPTGAPAQPPMLGTTTRPGTGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVAGGKASEPLLSPPPFGESRKSLEVKKEELGASSPGYGPPNLGCVDSPSAGPHLGGLELKAPDVFKAPLTPRASQVEPQSPGLGLRAQEPPPAQALAPSPPSHPDVFRSGPYPDPYAQPPLTPRPQPPPPESCCAPPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGPLAHTPLGAGGFPAALPSGPAGELHAKVPSGQPTNFARSPGTGTFVGTPSPMRFTFPQGVGEPSLKPPVPQPGLPSPHGINSHFGPGPTLGKPQSTNYAVATGNFHPSGSPLGPNSGPTGEGYGLSPLRPASVLPPPAPDGSLPYLTHGASQRVGITSPVEKREDPGATMSSSSLATPELSSAQDAGISSLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGNWGAEPSSPAFEQLSRGQTPFTGSQDRSSIVGLPASKLGGPTLGPGAFSSDDRLARPLPPATPSSMDMNSRQLVGGSQAFYQRTPYPGSLPLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLWQQQQQQQQQQQQQAAAAAAATSMRLAMSARFPSTPGPELGRQALGSPLAGIPTRLPGPAEPVPGPAGPAQFIELRHNVQKGLGPGVSPFPGQGPPQRPRFYPVSEELHRLAPEGLRGLAVPGLPSQKPSALPAPELNNSLHQTPHAKGPALASGLELVSRPPSNTELSRPPLALEAGKLPCEDPELDDDFDAHKALEDDEELAHLGLGVDVAKGDDELGTLENLETNDPHLDDLLNGDEFDLLAYTDPELDTGDKKDIFNEHLRLVESANEKAEREALLRGVEPVSLGPEERPPPAPDNSEPRLTSVLPEVKPKVEEGGRHPSPCQFTINTPKVEPAPPATSLSLGLKPGQTVMGTRDTRGGVGTGSFPSSGHTAEKGPFGATGGTPAHLLNPSSLSGPAASSLLEKFELESGALTLPSGHAAAGDELDKMESSLVASELPLLIEDLLEHEKKELQKKQQLSAQTVLPAQQQQQQQQQQQQQQQQHTLLPTPGPAQALPLPHEPGPPQQLALGIGSTRQPGLGQSMVPIQPPAHALQQRLAPSVAMVSNQGHMLSGQQAGQTGLVPQQSSQPVLAQKPMSAMPASMCMKPQQLAMQQQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGSIGVAPGMNRQQVSLLAQRLSGGSGSDLQNHVAPGSGQERNAGDPAQPRPNPPTFAQGVINEADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQQHSAVLAVSPSQNPRVLTKLPGQLLPAHGLQPPQAPPGGQAGGLRLPPGGMVLPGQSGGPFLNTTLAQQQQQQHSGVAGSLTGPPGSFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQQQQHLLGQVAIQQQQGPGVQNQALGPKPQGLLPPSNHQGLLVQQLSPQQSQGSQGLLGPAQVTVLQQQQQQQQHSGALGPQGPHRQVLMTQSRVLSSPQLAQQGHSLMGHRLLTAQQQQQQQQQQQQQQQQQQQQQQQQQGSMTGLSQLQQGMMSHGGQPKMSAQALGSLQQQQQQLQQQQMLQQQQLQQQQQQLQQQQQQQQLQQQQQQQLQLQQQQQQQQQHLQHQQQQQQQLQQQQQLQQQQQQQLHLQQQLHQQQQLQLQQQQMGLLNQNRTLLSPQQQQQQQQQQQQQQQQQQQQQQQQQQVTLGPGLPVKPLQHFSSSGALGPTLLLTGKEQNNAETALPSEVTEGPSTHQGGPPAVGTAPEPMSVEPGEVKPSISGDSQLLLVQSQAQSQATSVQLQPPLRLPGQPQPQVNLLHTAGGGSHGQQLGSGSSSESPAVPHLLAQPSVSLGEQPGPMAQNLLGSQQPLGLDRPIQNNTGSQPPKSGPAPQSGQGPPGAGVMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPFQEPGTQPSPLQGLLGCQPQPGGFSVSQTGPLQELGAGSRPQGPPRLPVPQGALSTGPVLGPAHPTPPPSSPQEPKRPSQLPSPSAQLTPTHPGTPKPQGPALELPPGRVSPAAAQLADTFFGKGLGPWDPSDNLTEAQKPEQSSLVPGHLDQVNGQVVHEPSQLSIKQEPREEPCALGAQTVKREANGEPAGAPGTSNHLLLAGSRSEAGHLLLQKLLRAKNVQLGAGRGPEGLRAEINGHIDSKLSGLEQKLQGTSSNKEDAATRKPLPAKPKRVQKTSDRLPSSRKKLRKEDGVRANEALLKQLKQELSQLPLTEPTITANFSLFAPFGSGCLVSGQSQLRGAFGSGALHTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSDELGERPKDTASAQDSEGALRDAAEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPQLGSGRWEQDNRALSPVIPIIPRTGIPVFPDTKPYGVLDLEVPGKLPATAWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPDGPARAGLEPKKGEAEGPGGKEKGLSGKGPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPSIQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPAEPMVELQAERPAEPPIPSPLPLASSPESARPKPRARPPEESEDSRPPRLKKWKGVRWKRLRLLLTIQKGSGHQEDEREVAEFMEQFGTALRPSKVPRDNRRCCFCHEEGDGATDGPARLLNLDLDLWVHLNCALWSTEVYETQGGALMNVEVALHRGLLTKCSLCQRTGATSSCNRMRCPNVYHFACAIRAKCMFFKDKTMLCPVHKIKGPCEQELSSFAVFRRVYIERDEVKQIASIIQRGERLHMFRVGGLVFHAIGQLLPHQMADFHSATALYPVGYEATRIYWSLRTNNRRCCYRCSISENNGRPEFVIKVIEQGLEDLVFTDASPQAVWNRIIEPVAAMRKEADMLRLFPEYLKGEELFGLTVHAVLRIAESLPGVESCQNYLFRYGRHPLMELPLMINPTGCARSEPKILTHYKRPHTLNSTSMSKAYQSTFTGETNTPYSKQFVHSKSSQYRRLRTEWKNNVYLARSRIQGLGLYAAKDLEKHTMVIEYIGTIIRNEVANRREKIYEEQNRGIYMFRINNEHVIDATLTGGPARYINHSCAPNCVAEVVTFDKEDKIIIISSRRIPKGEELTYDYQFDFEDDQHKIPCHCGAWNCRKWMN
Tissue specificity：
Induction：
Developmental stage：
Protein families：Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, TRX/MLL subfamily