NF2L1_MOUSE Q61985
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UniProt:Q61985
Recommended name：Endoplasmic reticulum membrane sensor NFE2L1
EC number：
Alternative names：(Locus control region-factor 1) (LCR-F1) (Nuclear factor erythroid 2-related factor 1) (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1)
Cleaved into：Transcription factor NRF1
GeneID：18023
Gene names (primary )：Nfe2l1
Gene names (synonym )：Nrf1
Gene names (ORF )：
Length：741
Mass：81575
Sequence：MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQLPPLREIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFTARRLLSQVRALDRFQVPTTEVNAWLVHRDPEGSVSGSQPNSGLALESSSGLQDVTGPDNGVRESETEQGFGEDLEDLGAVAPPVSGDLTKEDIDLIDILWRQDIDLGAGREVFDYSHRQKEQDVDKELQDGREREDTWSGEGAEALARDLLVDGETGESFPAQFPADVSSIPEAVPSESESPALQNSLLSPLLTGTESPFDLEQQWQDLMSIMEMQAMEVNTSASEILYNAPPGDPLSTNYSLAPNTPINQNVSLHQASLGGCSQDFSLFSPEVESLPVASSSTLLPLVPSNSTSLNSTFGSTNLAGLFFPSQLNGTANDTSGPELPDPLGGLLDEAMLDEISLMDLAIEEGFNPVQASQLEEEFDSDSGLSLDSSHSPSSLSSSEGSSSSSSSSSSSSASSSASSSFSEEGAVGYSSDSETLDLEEAEGAVGYQPEYSKFCRMSYQDPSQLSCLPYLEHVGHNHTYNMAPSALDSADLPPPSTLKKGSKEKQADFLDKQMSRDEHRARAMKIPFTNDKIINLPVEEFNELLSKYQLSEAQLSLIRDIRRRGKNKMAAQNCRKRKLDTILNLERDVEDLQRDKARLLREKVEFLRSLRQMKQKVQSLYQEVFGRLRDEHGRPYSPSQYALQYAGDGSVLLIPRTMADQQARRQERKPKDRRK
Tissue specificity：Isoform 1: Widely expressed including kidney, brown fat, white fat, large intestine, small intestine, stomach, lung, brain and liver (PubMed:23144760). Isoform 1: Expressed in mouse embryonic fibroblasts (MEF) (PubMed:23144760). Isoform 2: Widely expressed including kidney, brown fat, white fat, large intestine, small intestine, stomach, lung, brain and liver (PubMed:23144760). Isoform 2: levels in white fat, lung and liver are increased compared to isoform 1 (at protein level) (PubMed:23144760). Isoform 2: levels are elevated in brown fat and brain, but are reduced in liver compared to isoform 1 levels (PubMed:23144760). Isoform 2: Expressed in mouse embryonic fibroblasts (MEF) (PubMed:23144760). {ECO:0000269|PubMed:23144760}.
Induction：
Developmental stage：
Protein families：BZIP family, CNC subfamily