LCTL_MOUSE Q8K1F9
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UniProt:Q8K1F9
Recommended name：Lactase-like protein
EC number：
Alternative names：(Klotho/lactase-phlorizin hydrolase-related protein)
Cleaved into：
GeneID：235435
Gene names (primary )：Lctl
Gene names (synonym )：Klph
Gene names (ORF )：
Length：566
Mass：64826
Sequence：MKPVWVIILGWILLVPRVGTAWRGPPEEASFYYGTFPPGFSWGVGSSAYQTEGAWDEDGKGPSIWDAFTHGRKEQVLGGDTADTACDSYYKVQEDIALLKELQVSHYRFSLSWPRLLPTGVRAEQVNKRGIKFYSDFIDALLKSNITPVVTLHHWDLPQMLQVAYGGWQNVSMTRYFSDYADLCFEVFGDRVKHWLTFSDPRTMVEKGYETGLHAPGLRLQGTGLYVAAHHIIKAHAQAWHSYNNTWRSKQHGLVGISLNCDWGEPVDIDNPDDIEAAERYLQFCLGWFANPIYAGDYPQVMKDHIGTKSAEQGLEMSRLPTFSLQEKSYLKGTSDFLGLGHFTTRYITQRKYPSHQGPSYQNDRDLVELVDPNWPEMGSPWLYSVPWGFRRLLNFAQTQYGDPPIYVTESGAPQKLHCTQFCDEWRIQYLKGYINEMLKAIKDGVDIKGYTSWSLLDKFEWEKGYADKYGFYYVEFNVRNKPRYPKASVQYYKEIITASGFPNPQEVESWRLKALETCSINNQMLATEPLLRHMHVASEIVVPTVCALSILTAALMLTLLLRRRG
Tissue specificity：Strongly expressed in the lens of the eye, where it localizes to the equatorial epithelium and outer layers of newly extending fiber cells (at protein level) (PubMed:29425878). May also be expressed in kidney and skin (PubMed:12084582). However, another study suggests that expression is specific to eye and is minimal in other tissues (PubMed:29425878). {ECO:0000269|PubMed:12084582, ECO:0000269|PubMed:29425878}.
Induction：
Developmental stage：
Protein families：Glycosyl hydrolase 1 family, Klotho subfamily