I23O2_MOUSE Q8R0V5
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UniProt:Q8R0V5
Recommended name:Indoleamine 2,3-dioxygenase 2
EC number:EC 1.13.11.-
Alternative names:(IDO-2) (Indoleamine 2,3-dioxygenase-like protein 1) (Indoleamine-pyrrole 2,3-dioxygenase-like protein 1)
Cleaved into:
GeneID:209176
Gene names (primary ):Ido2
Gene names (synonym ):Indol1
Gene names (ORF ):
Length:405
Mass:45255
Sequence:MEPQSQSMTLEVPLSLGRYHISEEYGFLLPNPLEALPDHYKPWMEIALRLPHLIENRQLRAHVYRMPLLDCRFLKSYREQRLAHMALAAITMGFVWQEGEGQPQKVLPRSLAIPFVEVSRNLGLPPILVHSDLVLTNWTKRNPEGPLEISNLETIISFPGGESLRGFILVTVLVEKAAVPGLKALVQGMEAIRQHSQDTLLEALQQLRLSIQDITRALAQMHDYVDPDIFYSVIRIFLSGWKDNPAMPVGLVYEGVATEPLKYSGGSAAQSSVLHAFDEFLGIEHCKESVGFLHRMRDYMPPSHKAFLEDLHVAPSLRDYILASGPGDCLMAYNQCVEALGELRSYHINVVARYIISAATRARSRGLTNPSPHALEDRGTGGTAMLSFLKSVREKTMEALLCPGA
Tissue specificity:Expressed mainly in antigen-presenting immune cells, liver, kidney, brain, and placenta (PubMed:25691885, PubMed:17671174). Highly expressed in kidney, followed by epididymis and liver (at protein level) (PubMed:17499941). Detected in the tails of the spermatozoa in the testis and in the kidney tubules (at protein level) (PubMed:17499941). Constitutively expressed in brain. {ECO:0000269|PubMed:17499941, ECO:0000269|PubMed:17671174, ECO:0000303|PubMed:25691885}.
Induction:
Developmental stage:
Protein families:Indoleamine 2,3-dioxygenase family