I23O2_MOUSE   Q8R0V5


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UniProt:Q8R0V5

Recommended name:Indoleamine 2,3-dioxygenase 2

EC number:EC 1.13.11.-

Alternative names:(IDO-2) (Indoleamine 2,3-dioxygenase-like protein 1) (Indoleamine-pyrrole 2,3-dioxygenase-like protein 1)

Cleaved into:

GeneID:209176

Gene names  (primary ):Ido2

Gene names  (synonym ):Indol1

Gene names  (ORF ):

Length:405

Mass:45255

Sequence:MEPQSQSMTLEVPLSLGRYHISEEYGFLLPNPLEALPDHYKPWMEIALRLPHLIENRQLRAHVYRMPLLDCRFLKSYREQRLAHMALAAITMGFVWQEGEGQPQKVLPRSLAIPFVEVSRNLGLPPILVHSDLVLTNWTKRNPEGPLEISNLETIISFPGGESLRGFILVTVLVEKAAVPGLKALVQGMEAIRQHSQDTLLEALQQLRLSIQDITRALAQMHDYVDPDIFYSVIRIFLSGWKDNPAMPVGLVYEGVATEPLKYSGGSAAQSSVLHAFDEFLGIEHCKESVGFLHRMRDYMPPSHKAFLEDLHVAPSLRDYILASGPGDCLMAYNQCVEALGELRSYHINVVARYIISAATRARSRGLTNPSPHALEDRGTGGTAMLSFLKSVREKTMEALLCPGA

Tissue specificity:Expressed mainly in antigen-presenting immune cells, liver, kidney, brain, and placenta (PubMed:25691885, PubMed:17671174). Highly expressed in kidney, followed by epididymis and liver (at protein level) (PubMed:17499941). Detected in the tails of the spermatozoa in the testis and in the kidney tubules (at protein level) (PubMed:17499941). Constitutively expressed in brain. {ECO:0000269|PubMed:17499941, ECO:0000269|PubMed:17671174, ECO:0000303|PubMed:25691885}.

Induction:

Developmental stage:

Protein families:Indoleamine 2,3-dioxygenase family


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