IF2G_MOUSE   Q9Z0N1


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UniProt:Q9Z0N1

Recommended name:Eukaryotic translation initiation factor 2 subunit 3, X-linked

EC number:EC 3.6.5.3

Alternative names:(Eukaryotic translation initiation factor 2 subunit gamma, X-linked) (eIF-2-gamma X)

Cleaved into:

GeneID:26905

Gene names  (primary ):Eif2s3x

Gene names  (synonym ):

Gene names  (ORF ):

Length:472

Mass:51065

Sequence:MAGGEGGVTLGQPHLSRQDLATLDVTKLTPLSHEVISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDPSCPRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPPRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKPTVDDD

Tissue specificity:Widely expressed. In the brain, high mRNA levels are observed in specific regions, including the habenula, anterodorsal thalamic nucleus, hippocampus, hypothalamus, and cerebellum. Also expressed in the embryonic brain. There is a differential expression between males and females, wich is tissue-specific. Females tend to have higher expression levels than males in the brain (cortex, hippocampus and paraventricular nucleus, but not in the habenula), as well as in other tissues. The up-regulation observed in females at the mRNA level may be due to the presence of 2 active copies of the gene. {ECO:0000269|PubMed:12023983, ECO:0000269|PubMed:16325480, ECO:0000269|PubMed:9736774}.

Induction:

Developmental stage:

Protein families:TRAFAC class translation factor GTPase superfamily, Classic translation factor GTPase family, EIF2G subfamily


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