TTBK1_MOUSE Q6PCN3
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UniProt:Q6PCN3
Recommended name：Tau-tubulin kinase 1
EC number：EC 2.7.11.1
Alternative names：
Cleaved into：
GeneID：106763
Gene names (primary )：Ttbk1
Gene names (synonym )：
Gene names (ORF )：
Length：1308
Mass：141613
Sequence：MQCLAAALKDETNMSGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWEKAGTDALLSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQGEHLSDQENAPPILPGRPPEGLGPGPHLVPHPGGPEAEVWEETDVNRNKLRINIGKTPCVEEEQSRGVGVPSSPVRAPPDSPTTPVRSLCYRRVNSPESERLSTAADGRVELQERRSRMDLPGSPSRQACSSQPAQMLSVDTGHADRQASGRMDVSASVEQEALSNAFRSVPLAEEEDFDSKEWVIIDKETELKDFPPGAEPSTSGTTDEEPEELRPLPEEGEERRRLGTEPTVRPRGRGMHTLTEEDPRQMLPQPAPPQLSQADGRSETSQPPTPGSPSHSPLHSGPRPRRRESDPTGPQRQVFSVAPPFEVNGLPRAVPLALPYQDFKRDLSDYRERARLLNRVRRVGFSHMLLTAPQVPLAPFQPQANGKEGEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAGALGEVLGPRSGSSSEGSERSTERSQEGAPSTLLADDQKEARGRASMADGDLEPEEGSKTLVLVSPGDMKKSPVTAELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSILKSEPKPSGPGAGGGVGLVAPGAGVTAVTSPFTKVERTFVHIAEKSHLNVMSSGGQASRPEELSTGGELGLEVLSEGGIAEEGAPAPLENGMALAGLDGTEMESCALSGPPGETPSEVVTDSLPNGPALADGPAPASQQEPVTKKGTTISPSRHAMPGSRPRSRIPVLLSEEDTGSEPSGSLSAKERWSKRARPQQDLARLVMEKRQGRLLLRLASGASSSSSEEQRRASETLSGTGSEEDTPASEPTTALPRKAVRAATTRSRIPRPISVSMPVEGQQLPGRPHGAASATDLAITSRLQLQKPSGLAPAADLRPKQSASRGPGPGRAQVSKPAAPRSPGLPASTARHPSGSPRSQSLSRKESSSPSHQARPGVPPSRGVLQVRSQPEASPVAPKKGPKGKQLQTQRAATKGRAVVSEGRPGAR
Tissue specificity：Expressed in the brain. Strong expression in the cortical layers, the CA1 layers of the hippocampus and the granular layer of the cerebellum. Also expressed in the large cortical pyramidal cells in the temporal cortex, the CA1 pyramidal neurons and the cerebellum granular neurons. {ECO:0000269|PubMed:16923168}.
Induction：
Developmental stage：
Protein families：Protein kinase superfamily, CK1 Ser/Thr protein kinase family