DGKH_MOUSE   D3YXJ0


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UniProt:D3YXJ0

Recommended name:Diacylglycerol kinase eta

EC number:EC 2.7.1.107

Alternative names:(DAG kinase eta) (Diglyceride kinase eta) (DGK-eta)

Cleaved into:

GeneID:380921

Gene names  (primary ):Dgkh

Gene names  (synonym ):

Gene names  (ORF ):

Length:1211

Mass:134132

Sequence:MAGAGSQHHPQGVAGGAVAGASAVSPTAAGPGEDSSDSEAEQEGPQKLIRKVSTSGQMRTKTSIKEGQLLKQTSSFQRWKKRYFKLRGRTLYYAKDSKSLIFDEVDLSDASVAEASTKNANNSFTIITPFRRLMLCAENRKEMEVWISSLKSVQSREPYEVAQFNVEHFSGMHNWYACSHARPTFCNVCRESLSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDEDGVAMPHQWLEGNLPVSAKCAVCDKTCGSVLRLQDWKCLWCKTMVHTACKDVYHPVCPLGQCKVSIIPPIALNSTDSDGFCRATFSFCVSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPYLGLRLFQKFDNFRILVCGGDGSVGWVLSEIDKLNLHKQCQLGVLPLGTGNDLARVLGWGGSYDDDTQLPQILEKLERASTKMLDRWSIMTYELKLPAKSSLLPEPVAATEEFYMTIYEDSVANHLTKIVNSDEHAVVISSAKILCETVKDFVAKVEKAQDRTLENTVVAEAVASKCSVLNEKLEQLLQALHADSQASRVPPGIGPAIPEEDTVESASDESLGESKDQLVNDIGKPSSQKAVKPREIMLRANSLKKAVRQVIEEAEKVMDEPAVQPSEPVSPSCDYDTETDEAKEDDAKESLSAKTTSQSPDAQASCGHPQTDSVAGPAMATTKENLPVLNTRIICPGLRAGLAASIAGSSIINKMLLANIDPFGATPFIDPDLDSLDGYSEKCVMNNYFGIGLDAKISLEFNNKREEHPEKCRSRTKNLMWYGVLGTRELLQRSYKNLEQRVQLECDGQYIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDIFAAPSFDDKILEVVAVFDSVQMAVSRVIKLQHHRIAQCRTVKITIFGDEGVPVQVDGEAWVQPPGIIKIVHKNRAQMLTRDRAFESTLKSWEDKQKCDSGKPVLRTNLYIHPAPDLATEEVSQMRLCSQAAEELITRICDAATIHCLLEQELAHAVNACSHALNKANPRFPESLTRDTATEIAINVKALYNETEALLVGRVPLHLESPHEERVSSALHSVEMELQKLTEIPWLYYILRPSEDEEPPLDCTKRNNKSTVFRIVPKFKKEKAQKQKTSSQPVQNWGTEEVAAWLDLLNLGEYKEIFIRHDVRGAELLHLERRDLKDLGIPKVGHMKRILQGIKELERNPPNLV

Tissue specificity:Widely expressed (PubMed:27643686). Detected in the granulosa cells of the primary and secondary follicles (PubMed:25613821). Expressed in mature follicles and corpus lutea (PubMed:25613821). Expressed in the oviductal epithelium (PubMed:25613821). In the uterus, strongly expressed in the luminal epithelium (PubMed:25613821). Detected in the uterine glands (PubMed:25613821). {ECO:0000269|PubMed:25613821, ECO:0000269|PubMed:27643686}.; [Isoform 2]: Detected in ovary and uterus (at protein level). {ECO:0000269|PubMed:25613821}.; [Isoform 3]: Specifically expressed in testis (PubMed:25613821, PubMed:27643686). Detected in the inner area of the testis (PubMed:25613821). Strongly expressed in the secondary spermatocytes and the round spermatids and weakly detected in the primary spermatocytes (PubMed:25613821). {ECO:0000269|PubMed:25613821, ECO:0000269|PubMed:27643686}.

Induction:

Developmental stage:

Protein families:Eukaryotic diacylglycerol kinase family


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