DGKE_MOUSE Q9R1C6
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UniProt:Q9R1C6
Recommended name:Diacylglycerol kinase epsilon
EC number:EC 2.7.1.107
Alternative names:(DAG kinase epsilon) (Diglyceride kinase epsilon) (DGK-epsilon)
Cleaved into:
GeneID:56077
Gene names (primary ):Dgke
Gene names (synonym ):
Gene names (ORF ):
Length:564
Mass:63635
Sequence:MEGDQRSGPPAQSLLPDGHLVLWTLCSVLLPVFITLWCSLQRSRRQLHRRDIFRKSKHCWRDTDLFSHPTYCCVCAQHILQGAFCDCCGLRVDEGCLKKVDKRFPCKEIMLKNDKAADAMPHHWIRGNVPLCSYCVFCRQQCGSQPKLCDYRCIWCQKTVHDECMRGSLRSEKCDFGEFRNLIIPPSYLTSINQMRKDKNTNYEGLASKFGKQWTPLIILANSRSGTNMGEGLLGEFKILLNPVQVFDVTKTPPIKALQLCTLLPYYSVRVLVCGGDGTVGWVLDAIDEMKIKGQEKYIPEVAVLPLGTGNDLSNTLGWGTGYAGEIPVAQVLRNVMEADGIKLDRWKVQVTNKGYYNLRKPKEFTMNNYFSVGPDALMALNFHAHREKAPSLFSSRILNKAVYLFYGTKDCLVQECKDLNKKIELELDGERVELPNLEGIIVLNIGYWGGGCRLWEGMGDETYPLARHDDGLLEIVGVYGSFHCAQIQVKLANPFRIGQAHTVRLTLKCSMMPMQVDGEPWAQGPCTVTITHKTHALMLYFSGEQSDDDISSPSDHEDVKEAE
Tissue specificity:Highly expressed in brain and heart (PubMed:11287665). In brain, highly expressed in Purkinje cells of the cerebellum, pyramidal cells of the hippocampus, mitral cells of the olfactory bulb, and neurons of the substantia nigra (PubMed:11287665). Lower expression in neurons of the thalamus, superior olive, and lateral reticular nucleus is also detected (PubMed:11287665). Expressed in platelets (PubMed:23542698). {ECO:0000269|PubMed:11287665, ECO:0000269|PubMed:23542698}.
Induction:
Developmental stage:
Protein families:Eukaryotic diacylglycerol kinase family