CHK2_MOUSE Q9Z265
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UniProt:Q9Z265
Recommended name:Serine/threonine-protein kinase Chk2
EC number:EC 2.7.11.1
Alternative names:(CHK2 checkpoint homolog) (Checkpoint kinase 2)
Cleaved into:
GeneID:50883
Gene names (primary ):Chek2
Gene names (synonym ):Chk2 Rad53
Gene names (ORF ):
Length:546
Mass:61088
Sequence:MKSHHQSHSSTSSKAHDSASCSQSQGGFSQPQGTPSQLHELSQYQGSSSSSTGTVPSSSQSSHSSSGTLSSLETVSTQELCSIPEDQEPEEPGPAPWARLWALQDGFSNLDCVNDNYWFGRDKSCEYCFDGPLLRRTDKYRTYSKKHFRIFREMGPKNCYIVYIEDHSGNGTFVNTELIGKGKRCPLSNNSEIALSLCRNKVFVFFDLTVDDQSVYPKELRDEYIMSKTLGSGACGEVKMAFERKTCQKVAIKIISKRRFALGSSREADTAPSVETEIEILKKLNHPCIIKIKDVFDAEDYYIVLELMEGGELFDRVVGNKRLKEATCKLYFYQMLVAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGQSKILGETSLMRTLCGTPTYLAPEVLVSNGTAGYSRAVDCWSLGVILFICLSGYPPFSEHKTQVSLKDQITSGKYNFIPEVWTDVSEEALDLVKKLLVVDPKARLTTEEALNHPWLQDEYMKKKFQDLLVQEKNSVTLPVAPAQTSSQKRPLELEVEGMPSTKRLSVCGAVL
Tissue specificity:Ubiquitously expressed with higher levels in the thymus, spleen and colon (at protein level). {ECO:0000269|PubMed:12192050}.
Induction:
Developmental stage:
Protein families:Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily