CHK2_MOUSE   Q9Z265


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UniProt:Q9Z265

Recommended name:Serine/threonine-protein kinase Chk2

EC number:EC 2.7.11.1

Alternative names:(CHK2 checkpoint homolog) (Checkpoint kinase 2)

Cleaved into:

GeneID:50883

Gene names  (primary ):Chek2

Gene names  (synonym ):Chk2 Rad53

Gene names  (ORF ):

Length:546

Mass:61088

Sequence:MKSHHQSHSSTSSKAHDSASCSQSQGGFSQPQGTPSQLHELSQYQGSSSSSTGTVPSSSQSSHSSSGTLSSLETVSTQELCSIPEDQEPEEPGPAPWARLWALQDGFSNLDCVNDNYWFGRDKSCEYCFDGPLLRRTDKYRTYSKKHFRIFREMGPKNCYIVYIEDHSGNGTFVNTELIGKGKRCPLSNNSEIALSLCRNKVFVFFDLTVDDQSVYPKELRDEYIMSKTLGSGACGEVKMAFERKTCQKVAIKIISKRRFALGSSREADTAPSVETEIEILKKLNHPCIIKIKDVFDAEDYYIVLELMEGGELFDRVVGNKRLKEATCKLYFYQMLVAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGQSKILGETSLMRTLCGTPTYLAPEVLVSNGTAGYSRAVDCWSLGVILFICLSGYPPFSEHKTQVSLKDQITSGKYNFIPEVWTDVSEEALDLVKKLLVVDPKARLTTEEALNHPWLQDEYMKKKFQDLLVQEKNSVTLPVAPAQTSSQKRPLELEVEGMPSTKRLSVCGAVL

Tissue specificity:Ubiquitously expressed with higher levels in the thymus, spleen and colon (at protein level). {ECO:0000269|PubMed:12192050}.

Induction:

Developmental stage:

Protein families:Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily


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