AZIN2_MOUSE Q8BVM4
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UniProt:Q8BVM4
Recommended name:Antizyme inhibitor 2
EC number:
Alternative names:(AzI2) (Arginine decarboxylase-like protein) (ADC) (ARGDC) (Ornithine decarboxylase-like protein) (ODC-like protein) (ornithine decarboxylase paralog) (ODC-p)
Cleaved into:
GeneID:242669
Gene names (primary ):Azin2
Gene names (synonym ):Adc Odcp
Gene names (ORF ):
Length:459
Mass:49503
Sequence:MAGYLSESDFVMVEEGFSTRDLLEELTLGASQATSGKVAAFFVADLGAVVRKHFCFLKHLPRVRPFYAVGCNSSLGVLKVLAELGLGFSCANKAEMELVQHIGVPASKIICANPCKQVAQIKYAAKHGVRLLSFDNEVELAKVVKSHPSAKMVLCIATQDSHSLNHLSLRFGASLKSCRHLLENAKKSHVEVVGVSFHIGSGCPDPQAYAQSIADARLVFQMGEELGHTMNILDLGGGFPGLEGAKVRFEEMASVINSALDLYFPEGCGVDILAELGRYYVTSAFTVAVSIVAKREVLDQASREEQTGAAPKSIVYYLDEGVYGVFNSVLFDNTCPTPALQKKPSADQPLYSSSLWGPAVEGCDCVAEGLWLPQLQVGDWLVFDNMGAYTVDTKSLLGGTQARRVTYAMSRLAWEALRGQLLPAEEDQDAEGVCKPLSCGWEITDTLCVGPVFTPASIM
Tissue specificity:Expressed in the medulla and chromaffin cells of the adrenal gland. Expressed in the Langerhans islets of the pancreas. Expressed in the inner part of the seminiferous tubules and in spermatozoa located in the lumen of the epididymis of the testis. Expressed in the cortex, hippocampus and cerebellum of the brain. Expressed in normal and neoplastic mast cells (MC) (at protein level). Expressed in testis, pancreas and brain. Expressed throughout the differentiation process from spermatids to spermatozoa in the inner part of the seminiferous tubules. Expressed in the kidney: expressed in the superficial (Cs) and the deep layer (Cd) of the cortex region and in the outer stripe (OS), inner stripe (IS) and the inner medulla papilla (IM) of the medulla region. {ECO:0000269|PubMed:16916800, ECO:0000269|PubMed:18508777, ECO:0000269|PubMed:18973822, ECO:0000269|PubMed:22562773, ECO:0000269|PubMed:23874910}.
Induction:
Developmental stage:
Protein families:Orn/Lys/Arg decarboxylase class-II family, ODC antizyme inhibitor subfamily