BACE2_MOUSE Q9JL18
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UniProt:Q9JL18
Recommended name：Beta-secretase 2
EC number：EC 3.4.23.45
Alternative names：(Aspartyl protease 1) (ASP1) (Asp 1) (Beta-site amyloid precursor protein cleaving enzyme 2) (Beta-site APP cleaving enzyme 2) (Memapsin-1) (Membrane-associated aspartic protease 1) (Theta-secretase)
Cleaved into：
GeneID：56175
Gene names (primary )：Bace2
Gene names (synonym )：
Gene names (ORF )：
Length：514
Mass：55800
Sequence：MGALLRALLLLVLAQWLLSAVPALAPAPFTLPLQVAGATNHRASAVPGLGTPELPRADGLALALEPVRATANFLAMVDNLQGDSGRGYYLEMLIGTPPQKVQILVDTGSSNFAVAGAPHSYIDTYFDSESSSTYHSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNSSFLVNIATIFESENFFLPGIKWNGILGLAYAALAKPSSSLETFFDSLVAQAKIPDIFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQNLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARTSLIPEFSDGFWTGAQLACWTNSETPWAYFPKISIYLRDENASRSFRITILPQLYIQPMMGAGFNYECYRFGISSSTNALVIGATVMEGFYVVFDRAQRRVGFAVSPCAEIEGTTVSEISGPFSTEDIASNCVPAQALNEPILWIVSYALMSVCGAILLVLILLLLLPLHCRHAPRDPEVVNDESSLVRHRWK
Tissue specificity：High expression in pancreatic islets. Expressed at much lower levels in the pituitary, colon, and ovaries and is nearly absent from all the other tissues. {ECO:0000269|PubMed:21907142}.
Induction：
Developmental stage：
Protein families：Peptidase A1 family