LOX12_MOUSE   P39655


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UniProt:P39655

Recommended name:Polyunsaturated fatty acid lipoxygenase ALOX12

EC number:EC 1.13.11.-

Alternative names:(Arachidonate (12S)-lipoxygenase) (12S-LOX) (12S-lipoxygenase) (Arachidonate (15S)-lipoxygenase) (Linoleate (13S)-lipoxygenase) (Lipoxin synthase 12-LO) (Platelet-type lipoxygenase 12) (P-12LO)

Cleaved into:

GeneID:11684

Gene names  (primary ):Alox12

Gene names  (synonym ):Alox12p

Gene names  (ORF ):

Length:663

Mass:75390

Sequence:MGRYRVRVVTGAWLFSGSLNLVRLWLVGEHREAKLELQLRPARGKEEEFDFDVPEDLGPLQFVKLHKQHTVVDDAWFCNLITVQGPGTSAEAVFPCYRWVQGEGILSLPEGTARLAGDNALDVFQKYREKELKERQQTYCWATWKEGLPQTIAADCKDDLPPNMRFHEEKRLDFEWTLKAGVLEMGLKRVYTLLRSWNHLEDFDQIFWGQKSALAEKVHQCWQEDELFGYQFLNGANPMLLRRSTSLPSRLVLPSGMEELQAQLEKELKNGSLFEADFILLDGIPANVIRGEPQYLAAPLVMLRMDPGGKLLPMAIQIQPPNPSSPAPTLFLPSDPPLAWLLAKIWVRNSDFQLQELQFHLLNTHLVAEVIAVATMRCLPGLHPIFKLLVPHIRYTMEINTRSRTQLISDGGIFDQVVSTGGGGHVQLLTRAVAQLTYHSLCPPDDLANRGLLRIPSALYARDALQLWEVTARYVKGMVHLFYQSDDIVRGDPELQAWCREITEVGLCHAQDRGFPVSFQSRAQLCHFLTMCVFTCTAQHAAINQGQLDWYGWVPNAPCTMRMPPPTSKDDVTMETVMGSLPDVQKACLQMTITWHLGRLQPDMVPLGHHTEKYFSDPRTKAVLSQFQADLDNLEKEITARNEQLDLPYEYLKPSRIENSITI

Tissue specificity:Found primarily in platelets and in microsomal and cytosolic fractions of the epidermis (at protein level). {ECO:0000269|PubMed:10383730, ECO:0000269|PubMed:8188678, ECO:0000269|PubMed:9501222}.

Induction:

Developmental stage:

Protein families:Lipoxygenase family


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