LOX12_MOUSE P39655
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UniProt:P39655
Recommended name:Polyunsaturated fatty acid lipoxygenase ALOX12
EC number:EC 1.13.11.-
Alternative names:(Arachidonate (12S)-lipoxygenase) (12S-LOX) (12S-lipoxygenase) (Arachidonate (15S)-lipoxygenase) (Linoleate (13S)-lipoxygenase) (Lipoxin synthase 12-LO) (Platelet-type lipoxygenase 12) (P-12LO)
Cleaved into:
GeneID:11684
Gene names (primary ):Alox12
Gene names (synonym ):Alox12p
Gene names (ORF ):
Length:663
Mass:75390
Sequence:MGRYRVRVVTGAWLFSGSLNLVRLWLVGEHREAKLELQLRPARGKEEEFDFDVPEDLGPLQFVKLHKQHTVVDDAWFCNLITVQGPGTSAEAVFPCYRWVQGEGILSLPEGTARLAGDNALDVFQKYREKELKERQQTYCWATWKEGLPQTIAADCKDDLPPNMRFHEEKRLDFEWTLKAGVLEMGLKRVYTLLRSWNHLEDFDQIFWGQKSALAEKVHQCWQEDELFGYQFLNGANPMLLRRSTSLPSRLVLPSGMEELQAQLEKELKNGSLFEADFILLDGIPANVIRGEPQYLAAPLVMLRMDPGGKLLPMAIQIQPPNPSSPAPTLFLPSDPPLAWLLAKIWVRNSDFQLQELQFHLLNTHLVAEVIAVATMRCLPGLHPIFKLLVPHIRYTMEINTRSRTQLISDGGIFDQVVSTGGGGHVQLLTRAVAQLTYHSLCPPDDLANRGLLRIPSALYARDALQLWEVTARYVKGMVHLFYQSDDIVRGDPELQAWCREITEVGLCHAQDRGFPVSFQSRAQLCHFLTMCVFTCTAQHAAINQGQLDWYGWVPNAPCTMRMPPPTSKDDVTMETVMGSLPDVQKACLQMTITWHLGRLQPDMVPLGHHTEKYFSDPRTKAVLSQFQADLDNLEKEITARNEQLDLPYEYLKPSRIENSITI
Tissue specificity:Found primarily in platelets and in microsomal and cytosolic fractions of the epidermis (at protein level). {ECO:0000269|PubMed:10383730, ECO:0000269|PubMed:8188678, ECO:0000269|PubMed:9501222}.
Induction:
Developmental stage:
Protein families:Lipoxygenase family