MIS_MOUSE P27106
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UniProt:P27106
Recommended name:Muellerian-inhibiting factor
EC number:
Alternative names:(Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance) (MIS)
Cleaved into:
GeneID:11705
Gene names (primary ):Amh
Gene names (synonym ):
Gene names (ORF ):
Length:555
Mass:59778
Sequence:MQGPHLSPLVLLLATMGAVLQPEAVENLATNTRGLIFLEDELWPPSSPPEPLCLVTVRGEGNTSRASLRVVGGLNSYEYAFLEAVQESRWGPQDLATFGVSSTDSQATLPALQRLGAWLGETGEQQLLVLHLAEVIWEPELLLKFQEPPPGGASRWEQALLVLYSGPGPQVTVTGTGLRGTQNLCPTRDTRYLVLTVDFPAGAWSGFGLILTLQPSREGATLSIDQLQAFLFGSDSRCFTRMTPTLVVLPPAEPSPQPAHGQLDTMPFPQPGLSLEPEALPHSADPFLETLTRLVRALRGPLTQASNTQLALDPGALASFPQGLVNLSDPAALGRLLDWEEPLLLLLSPTAATEREPIRLHGPASAPWAAGLQRRVAVELQAAASELRDLPGLPPTAPPLLARLLALCPNDSRSSGDPLRALLLLKALQGLRAEWHGREGRGRTRAQRGDKGQDGPCALRELSVDLRAERSVLIPETYQANNCQGACRWPQSDRNPRYGNHVVLLLKMQARGAALGRLPCCVPTAYAGKLLISLSEERISADHVPNMVATECGCR
Tissue specificity:Sertoli cells of fetal testes, and testes just after birth, but absent in adult testes. In female, AMH is expressed after birth in the granulosa cells of the follicle. AMH expression is dependent on the degree of follicular maturation and not on the age of the ovary.
Induction:
Developmental stage:
Protein families:TGF-beta family