LICH_MOUSE   Q9Z0M5


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UniProt:Q9Z0M5

Recommended name:Lysosomal acid lipase/cholesteryl ester hydrolase

EC number:EC 3.1.1.13

Alternative names:(Acid cholesteryl ester hydrolase) (LAL) (Cholesteryl esterase) (Lipase A) (Sterol esterase)

Cleaved into:

GeneID:16889

Gene names  (primary ):Lipa

Gene names  (synonym ):Lip1

Gene names  (ORF ):

Length:397

Mass:45325

Sequence:MQLQGLVFVFTIGILLSRVPTGTVSAVDPEVNMNVTEIIMRWGYPGEEHSVLTGDGYILSIHRIPRGRKNHFGKGPRPVVYLQHGLLADSSNWVTNIDNSSLGFLLADAGFDVWMGNSRGNTWSLKHKTLSVSQDEFWAFSFDEMAKYDLPASINYILNKTGQEQIYYVGHSQGCTIGFIAFSQMPELAKKIKMFLVLAPVLSLNFASGPLLQLGRLPDPLLKDMFGQKQFLPQSAMLKWLSIHVCTHVIMKELCANVFFLLCGFNEKNLNMSRVDVYTTHCPAGTSVQNMLHWGQVFKYRKLQAFDWGSSEKNYFHYNQSFPPSYNIKNMRLPTALWSGGRDWLADINDITILLTQIPKLVYHKNIPEWDHLDFIWGLDAPWKLYDEIISLMKKYQ

Tissue specificity:Expressed at low levels in most tissues. High level expression is found in hepatocytes and splenic and thymic cells. Very high level expression is observed in cells of the small intestinal villi, the zona fasciculata and reticularis of the adrenal cortex, pancreatic acini, and renal tubular epithelium. {ECO:0000269|PubMed:8725147}.

Induction:

Developmental stage:

Protein families:AB hydrolase superfamily, Lipase family


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