LCLT1_MOUSE   Q3UN02


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UniProt:Q3UN02

Recommended name:Lysocardiolipin acyltransferase 1

EC number:EC 2.3.1.-

Alternative names:(1-acylglycerol-3-phosphate O-acyltransferase 8) (1-AGP acyltransferase 8) (1-AGPAT 8) (Acyl-CoA:lysocardiolipin acyltransferase 1)

Cleaved into:

GeneID:225010

Gene names  (primary ):Lclat1

Gene names  (synonym ):Agpat8 Alcat1 Gm91 Lycat

Gene names  (ORF ):

Length:376

Mass:44400

Sequence:MVSWKGIYFILFLFAGSFFGSIFMLGPILPLMFINLSWYRWISSRLVATWLTLPVALLETMFGVRVVITGDAFVPGERSVIIMNHRTRVDWMFLWNCLMRYSYLRVEKICLKSSLKSVPGFGWAMQVAAFIFIHRKWKDDKSHFEDMIDYFCAIHEPLQLLIFPEGTDLTENNKARSNDFAEKNGLQKYEYVLHPRTTGFTFVVDRLREGKNLDAVHDITVAYPYNIPQTEKHLLLGDFPKEIHFHVQRYPADSLPTSKEDLQLWCHRRWEEKEERLRSFYQGEKNFHFTGQSTVPPCKSELRVLVVKLLSIVYWALFCSAMCLLIYLYSPVRWYFIISIVFFVLQERIFGGLEIIELACYRFLHKHPHLNSKKNE

Tissue specificity:Widely expressed with highest expression in heart, liver and E12.5 aorta-gonad-mesonephros and lower levels in the E16 fetal liver and adult bone marrow. In bone marrow, highest levels are found in B-cells compared with whole bone marrow, T-cells, erythrocytes, and granulocytes. {ECO:0000269|PubMed:15152008, ECO:0000269|PubMed:16620771, ECO:0000269|PubMed:17675553}.

Induction:

Developmental stage:

Protein families:1-acyl-sn-glycerol-3-phosphate acyltransferase family


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