LCLT1_MOUSE Q3UN02
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UniProt:Q3UN02
Recommended name:Lysocardiolipin acyltransferase 1
EC number:EC 2.3.1.-
Alternative names:(1-acylglycerol-3-phosphate O-acyltransferase 8) (1-AGP acyltransferase 8) (1-AGPAT 8) (Acyl-CoA:lysocardiolipin acyltransferase 1)
Cleaved into:
GeneID:225010
Gene names (primary ):Lclat1
Gene names (synonym ):Agpat8 Alcat1 Gm91 Lycat
Gene names (ORF ):
Length:376
Mass:44400
Sequence:MVSWKGIYFILFLFAGSFFGSIFMLGPILPLMFINLSWYRWISSRLVATWLTLPVALLETMFGVRVVITGDAFVPGERSVIIMNHRTRVDWMFLWNCLMRYSYLRVEKICLKSSLKSVPGFGWAMQVAAFIFIHRKWKDDKSHFEDMIDYFCAIHEPLQLLIFPEGTDLTENNKARSNDFAEKNGLQKYEYVLHPRTTGFTFVVDRLREGKNLDAVHDITVAYPYNIPQTEKHLLLGDFPKEIHFHVQRYPADSLPTSKEDLQLWCHRRWEEKEERLRSFYQGEKNFHFTGQSTVPPCKSELRVLVVKLLSIVYWALFCSAMCLLIYLYSPVRWYFIISIVFFVLQERIFGGLEIIELACYRFLHKHPHLNSKKNE
Tissue specificity:Widely expressed with highest expression in heart, liver and E12.5 aorta-gonad-mesonephros and lower levels in the E16 fetal liver and adult bone marrow. In bone marrow, highest levels are found in B-cells compared with whole bone marrow, T-cells, erythrocytes, and granulocytes. {ECO:0000269|PubMed:15152008, ECO:0000269|PubMed:16620771, ECO:0000269|PubMed:17675553}.
Induction:
Developmental stage:
Protein families:1-acyl-sn-glycerol-3-phosphate acyltransferase family