ARP21_MOUSE Q9DCB4
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UniProt:Q9DCB4
Recommended name:cAMP-regulated phosphoprotein 21
EC number:
Alternative names:(ARPP-21) (Regulator of calmodulin signaling) (Thymocyte cAMP-regulated phosphoprotein)
Cleaved into:
GeneID:74100
Gene names (primary ):Arpp21
Gene names (synonym ):Rcs Tarpp
Gene names (ORF ):
Length:807
Mass:88567
Sequence:MSEQGGLTPTILEEGQTEPESAPENGILKSESLDEEEKLELQRRLAAQNQERRKSKSGAGKGKLTRSLAVCEESSARSGGESHQDQESIHLQLSSFPSLQEEDKSRKDDSEREKEKDKNREKLSERPKIRMLSKDCSQEYTDSTGIDLHGFLINTLKNNSRDRMILLKMEQEMIDFIADSNNHYKKFPQMSSYQRMLVHRVAAYFGLDHNVDQTGKSVIINKTSSTRIPEQRFCEHLKDEKSEESQKRFILKRDNSSIDKEDNQNRMHPFRDDRRSKSIEEREEEYQRVRERIFAHDSVCSQESLFLDNSRLQEDMHICNETYKKRQLFRAHRDSSGRTSGSRQSSSETELRWPDHQRAWSSTDSDSSNRNLKPTMTKTASFGGITVLTRGDSTSSTRSAGKLSKTGSESSSSAGSSGSLSRTHPQSTALTSSVAAGSPGCMAYSENGMGGQVPPSSTSYILLPLESATGIPPGSILLNPHTGQPFVNPDGTPAIYNPPGSQQTLRGTVGGQPQQPPQQQPSPQPQQQVQASQPQMAGPLVTQREELAAQFSQLSMSRQSSGDTPEPPSGTVYPASLLPQTAQPQSYVITSAGQQLSTGGFSDSGPPISQQVLQAPPSPQGFVQQPPPAQMSVYYYPSGQYPTSTSQQYRPLASVQYSAQRSQQIPQTTQQAGYQPVLSGQQGFQGMMGVQQSAHSQGVMSSQQGAPVHGVMVSYPTMSSYQVPMTQGSQAVPQQTYQPPIMLPSQAGQGSLPATGMPVYCNVTPPNPQNNLRLMGPHCPSSTVPVMSASCRTNCGNVSNAGWQVKF
Tissue specificity:[Isoform 1]: Present at high levels in thymus and low levels in brain. In thymus, isoform 1 is specifically found in immature thymocytes (at protein level). {ECO:0000269|PubMed:11298339}.
Induction:[Isoform 1]: Down-regulated in thymocytes upon TCR engagement (at protein level). {ECO:0000269|PubMed:11298339}.
Developmental stage:
Protein families: