SMS1_MOUSE Q8VCQ6
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UniProt:Q8VCQ6
Recommended name:Phosphatidylcholine:ceramide cholinephosphotransferase 1
EC number:EC 2.7.8.27
Alternative names:(Protein Mob) (Sphingomyelin synthase 1) (Transmembrane protein 23)
Cleaved into:
GeneID:208449
Gene names (primary ):Sgms1
Gene names (synonym ):Tmem23
Gene names (ORF ):
Length:419
Mass:49317
Sequence:MLSARTMKEVVYWSPKKVADWLLENAMPEYCEPLEHFTGQDLINLTQEDFKKPPLYRVSSDNGQRLLDMIETLKMEHHMEAHKNGHANGHLSIGVDIPNPDGSFSIKTKPNGMPNGFRKEMIKIPMPEPERSQYPMEWGKTFLAFLYALSCFVLTTVMISVVHERVPPKEVQPPLPDTFFDHFNRVQWAFSICEINGMILVGLWLFQWLLLKYKSIISRRFFCIVGTLYLYRCITMYVTTLPVPGMHFNCSPKLFGDWEAQVRRIMKLIAGGGLSITGSHNMCGDYLYSGHTVMLTLTYLFIKEYSPRRLWWYHWICWLLSVVGIFCILLAHDHYTVDVVVAYYITTRLFWWYHTMANQQVLKEASQMNLLARVWWYRPFQYFEKNVQGIVPRSYHWPFPWPVVHLSRQVKYSRLVNDT
Tissue specificity:Isoform 1 is widely expressed, isoform 2 shows a more narrow distribution and isoform 3 is detected only in testis and heart. {ECO:0000269|PubMed:16226406}.
Induction:[Isoform 1]: Induced by TNF-alpha. {ECO:0000269|PubMed:16226406}.; [Isoform 2]: Induced by TNF-alpha. {ECO:0000269|PubMed:16226406}.
Developmental stage:
Protein families:Sphingomyelin synthase family