SCRB1_MOUSE Q61009
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UniProt:Q61009
Recommended name:Scavenger receptor class B member 1
EC number:
Alternative names:(SRB1) (SR-BI)
Cleaved into:
GeneID:20778
Gene names (primary ):Scarb1
Gene names (synonym ):Srb1
Gene names (ORF ):
Length:509
Mass:56754
Sequence:MGGSSRARWVALGLGALGLLFAALGVVMILMVPSLIKQQVLKNVRIDPSSLSFGMWKEIPVPFYLSVYFFEVVNPNEVLNGQKPVVRERGPYVYREFRQKVNITFNDNDTVSFVENRSLHFQPDKSHGSESDYIVLPNILVLGGSILMESKPVSLKLMMTLALVTMGQRAFMNRTVGEILWGYDDPFVHFLNTYLPDMLPIKGKFGLFVGMNNSNSGVFTVFTGVQNFSRIHLVDKWNGLSKIDYWHSEQCNMINGTSGQMWAPFMTPESSLEFFSPEACRSMKLTYNESRVFEGIPTYRFTAPDTLFANGSVYPPNEGFCPCRESGIQNVSTCRFGAPLFLSHPHFYNADPVLSEAVLGLNPNPKEHSLFLDIHPVTGIPMNCSVKMQLSLYIKSVKGIGQTGKIEPVVLPLLWFEQSGAMGGKPLSTFYTQLVLMPQVLHYAQYVLLGLGGLLLLVPIICQLRSQEKCFLFWSGSKKGSQDKEAIQAYSESLMSPAAKGTVLQEAKL
Tissue specificity:Expressed primarily in liver, ovary and adrenal gland, and, at lower levels in other non-placental steroidogenic tissues, including adipose tissue, mammary gland and testis (at protein level) (PubMed:8560269, PubMed:9254074, PubMed:9614139). Isoform 2 is expressed at lower levels than isoform 1 in liver, testis and adrenal gland (PubMed:9614139). At the mRNA, but not at the protein level, isoform 2 is the predominant isoform in testis (80%) (PubMed:9254074). {ECO:0000269|PubMed:8560269, ECO:0000269|PubMed:9254074, ECO:0000269|PubMed:9614139}.
Induction:Both isoform 1 and isoform 2 are up-regulated in response to adrenocorticotropic hormone (ACTH). {ECO:0000305|PubMed:9614139}.
Developmental stage:
Protein families:CD36 family