SCRB1_MOUSE   Q61009


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UniProt:Q61009

Recommended name:Scavenger receptor class B member 1

EC number:

Alternative names:(SRB1) (SR-BI)

Cleaved into:

GeneID:20778

Gene names  (primary ):Scarb1

Gene names  (synonym ):Srb1

Gene names  (ORF ):

Length:509

Mass:56754

Sequence:MGGSSRARWVALGLGALGLLFAALGVVMILMVPSLIKQQVLKNVRIDPSSLSFGMWKEIPVPFYLSVYFFEVVNPNEVLNGQKPVVRERGPYVYREFRQKVNITFNDNDTVSFVENRSLHFQPDKSHGSESDYIVLPNILVLGGSILMESKPVSLKLMMTLALVTMGQRAFMNRTVGEILWGYDDPFVHFLNTYLPDMLPIKGKFGLFVGMNNSNSGVFTVFTGVQNFSRIHLVDKWNGLSKIDYWHSEQCNMINGTSGQMWAPFMTPESSLEFFSPEACRSMKLTYNESRVFEGIPTYRFTAPDTLFANGSVYPPNEGFCPCRESGIQNVSTCRFGAPLFLSHPHFYNADPVLSEAVLGLNPNPKEHSLFLDIHPVTGIPMNCSVKMQLSLYIKSVKGIGQTGKIEPVVLPLLWFEQSGAMGGKPLSTFYTQLVLMPQVLHYAQYVLLGLGGLLLLVPIICQLRSQEKCFLFWSGSKKGSQDKEAIQAYSESLMSPAAKGTVLQEAKL

Tissue specificity:Expressed primarily in liver, ovary and adrenal gland, and, at lower levels in other non-placental steroidogenic tissues, including adipose tissue, mammary gland and testis (at protein level) (PubMed:8560269, PubMed:9254074, PubMed:9614139). Isoform 2 is expressed at lower levels than isoform 1 in liver, testis and adrenal gland (PubMed:9614139). At the mRNA, but not at the protein level, isoform 2 is the predominant isoform in testis (80%) (PubMed:9254074). {ECO:0000269|PubMed:8560269, ECO:0000269|PubMed:9254074, ECO:0000269|PubMed:9614139}.

Induction:Both isoform 1 and isoform 2 are up-regulated in response to adrenocorticotropic hormone (ACTH). {ECO:0000305|PubMed:9614139}.

Developmental stage:

Protein families:CD36 family


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