MPEG1_MOUSE A1L314
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UniProt:A1L314
Recommended name：Macrophage-expressed gene 1 protein
EC number：
Alternative names：(Macrophage gene 1 protein) (Mpg-1) (Perforin-2) (P-2) (Protein MPS1)
Cleaved into：
GeneID：17476
Gene names (primary )：Mpeg1
Gene names (synonym )：
Gene names (ORF )：
Length：713
Mass：78390
Sequence：MNSFMALVLIWMIIACAEADKPLGETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSDTAKDVRAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLMSQVATNTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGITLGVTIALGIVITLAIYGTRKYKKKEYQEIEEQESLVGSLATDATVLNGEEDPSPA
Tissue specificity：Expressed constitutively in a variety of cell types including macrophages, microglia, neutrophils, T cells, marginal zone B cells, keratinocytes, splenocytes and intestinal epithelial cells. {ECO:0000269|PubMed:26402460}.
Induction：By CSF1 in fetal liver macrophages (PubMed:7888681). By interferon-alpha, by interferon-beta, by interferon-gamma and by bacterial infection with E.coli and M.smegmatis in embryonic fibroblasts (PubMed:23257510). {ECO:0000269|PubMed:23257510, ECO:0000269|PubMed:7888681}.
Developmental stage：
Protein families：MPEG1 family