CLNK_MOUSE   Q9QZE2


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UniProt:Q9QZE2

Recommended name:Cytokine-dependent hematopoietic cell linker

EC number:

Alternative names:(Mast cell immunoreceptor signal transducer)

Cleaved into:

GeneID:27278

Gene names  (primary ):Clnk

Gene names  (synonym ):Mist

Gene names  (ORF ):

Length:435

Mass:49492

Sequence:MTSQGNKRTTKEGFGDLRFQNVSLLKNRSWPSLSSAKGRCRAVLEPLPDHRRNLAGVPGGEKCNSNNDYEDPEFQLLKAWPSMKILPARPIQESEYADTRYFQDTMEAPLLLPPKASVSTERQTRDVRMTHLEEVDKPTFKDVRSQRFKGFKYTKINKTPLPPPRPAITLPKKYQPLPPAPPEESSAYFAPKPTFPEVQRGPRQRSAKDFSRVLGAEEESHHQTKPESSCPSSNQNTQKSPPAIASSSYMPGKHSIQARDHTGSMQHCPAQRCQAAASHSPRMLPYENTNSEKPDPTKPDEKDVWQNEWYIGEYSRQAVEDVLMKENKDGTFLVRDCSTKSKAEPYVLVVFYGNKVYNVKIRFLESNQQFALGTGLRGNEMFDSVEDIIEHYTYFPILLIDGKDKAARRKQCYLTQPLPLARLLLTQYSSQALHE

Tissue specificity:Expressed in T-cells, mast cells, natural killer and natural killer T cells (at protein level) (PubMed:10744659, PubMed:15199160, PubMed:16439675, PubMed:11509653). Expressed in cytokine-stimulated hemopoietic cells (PubMed:10562326). {ECO:0000269|PubMed:10562326, ECO:0000269|PubMed:10744659, ECO:0000269|PubMed:11509653, ECO:0000269|PubMed:15199160, ECO:0000269|PubMed:16439675}.

Induction:By cytokines such as IL2 and IL3 (PubMed:10562326, PubMed:15199160, PubMed:16439675). In natural killer T cells, by alpha-galactoceramide (PubMed:16439675). {ECO:0000269|PubMed:10562326, ECO:0000269|PubMed:15199160, ECO:0000269|PubMed:16439675}.

Developmental stage:

Protein families:


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