SIM20_MOUSE D3Z7Q2
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UniProt:D3Z7Q2
Recommended name:Small integral membrane protein 20
EC number:
Alternative names:(Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 7 kDa) (MITRAC7)
Cleaved into:Phoenixin-14 (PNX-14); Phoenixin-20 (PNX-20)
GeneID:66278
Gene names (primary ):Smim20
Gene names (synonym ):
Gene names (ORF ):
Length:69
Mass:7818
Sequence:MAAARNLRTALIFGGFISMVGAAFYPIYFRPLMRLEEYQKEQAVNRAGIVQEDVQPPGLKVWSDPFGRK
Tissue specificity:Highly expressed in the hypothalamus, the spinal cord, and sensory ganglia (at protein level) (PubMed:23912037, PubMed:26415767). Also expressed on in the epidermis and dermis layers of the skin (at protein level) (PubMed:26415767). Expressed in preadipocytes and adipocytes (at protein level) (PubMed:30251651). Expressed in the ovary, specifically in granulosa cells of follicles that have passed the primary stage and in oocytes (at protein level) (PubMed:30933929). {ECO:0000269|PubMed:23912037, ECO:0000269|PubMed:26415767, ECO:0000269|PubMed:30251651, ECO:0000269|PubMed:30933929}.
Induction:By fatty acids, specifically palmitate, docosahexanoic acid and oleate. {ECO:0000269|PubMed:30524225}.
Developmental stage:
Protein families: