PJA1_MOUSE   O55176


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UniProt:O55176

Recommended name:E3 ubiquitin-protein ligase Praja-1

EC number:EC 2.3.2.27

Alternative names:(Praja1) (RING-type E3 ubiquitin transferase Praja-1)

Cleaved into:

GeneID:18744

Gene names  (primary ):Pja1

Gene names  (synonym ):

Gene names  (ORF ):

Length:578

Mass:63906

Sequence:MSHQERIASQRRTTAEVPMHRSTANQSKRSRSPFASTRRRWDDSESSGASLAVESEDYSRYPPREYRASGSRRGLAYGHIDTVVARDSEEEGAGPVDRLPVRGKAGKFKDDPEKGARSSRFTSVNHDAKEECGKVESPPAARCSARRAELSKQNGSSASQISSAEGRAAAKGNNSLERERQNLPARPSRAPVSICGGGENTPKSAEEPVVRPKVRNVATPNCMKPKVFFDTDDDDDVPHSTSRWRDAADAEEAHAEGLARRGRGEAASSSEPRYAEDQDARSEQAKADKVPRRRRTMADPDFWAYTDDYYRYYEEDSDSDKEWMAALRRKYRSREQPQSSSGESWELLPGKEELERQQAGAGSLASAGSNGSGYPEEVQDPSLQEEEQASLEEGEIPWLRYNENESSSEGDNESTHELIQPGMFMLDGNNNLEDDSSVSEDLEVDWSLFDGFADGLGVAEAISYVDPQFLTYMALEERLAQAMETALAHLESLAVDVEVANPPASKESIDALPEILVTEDHGAVGQEMCCPICCSEYVKGEVATELPCHHYFHKPCVSIWLQKSGTCPVCRCMFPPPL

Tissue specificity:Expressed in brain, liver, kidney. Highest levels in brain where it is found in many regions including cortical and subcortical areas and in neurons of the amygdala. Weak expression also found in testis. Also expressed in developing embryo.

Induction:By fear memory. Differential induction of isoforms.

Developmental stage:

Protein families:


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