TRI63_MOUSE Q38HM4
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UniProt:Q38HM4
Recommended name:E3 ubiquitin-protein ligase TRIM63
EC number:EC 2.3.2.27
Alternative names:(Muscle-specific RING finger protein 1) (MuRF-1) (MuRF1) (Muscle RING finger protein 1) (RING-type E3 ubiquitin transferase TRIM63) (Tripartite motif-containing protein 63)
Cleaved into:
GeneID:
Gene names (primary ):Trim63
Gene names (synonym ):Murf1 Rf1
Gene names (ORF ):
Length:350
Mass:39491
Sequence:MDYKSGLIPDGNAMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAANPYWTNRGGSVSMSGGRFRCPSCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRPLQKGSHPMCKEHEDEKINIYCLTCEVPTCSLCKVFGAHQACEVAPLQSIFQGQKTELSNCISMLVAGNDRVQTIISQLVDSCRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQEEKLGFIEALILQYREQLEKSTKLVETAIQSLDEPGGATFLSSAKQLIKSNVEASKGCQLGKTEQGFENMDYFTLDLEHIAEALRAIDFGTDEEEEEFTEEEADEEEGVTTEGHQ
Tissue specificity:
Induction:By hydrogen peroxide. Up-regulated in response to amino acid starvation. {ECO:0000269|PubMed:12773310, ECO:0000269|PubMed:18222470}.
Developmental stage:
Protein families: