IKBZ_MOUSE Q9EST8
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UniProt:Q9EST8
Recommended name：NF-kappa-B inhibitor zeta
EC number：
Alternative names：(I-kappa-B-zeta) (IkB-zeta) (IkappaBzeta) (IL-1 inducible nuclear ankyrin-repeat protein) (INAP) (Molecule possessing ankyrin repeats induced by lipopolysaccharide) (MAIL)
Cleaved into：
GeneID：80859
Gene names (primary )：Nfkbiz
Gene names (synonym )：Inap Mail
Gene names (ORF )：
Length：728
Mass：79007
Sequence：MIVDKLLDDSRGGEGLLDAAGDCGLMTSPLNLAYFYGASPPSAPGAGDTGYLSAVPSAPGSPGSDSSDFSSTSSVSSCGAVESRPRGGARAERPQVEPHMGVGRQQRGPFQGVRVKNSVKELLLHIRSNKQKASGQPVDEFKTQSVNIEQLTDLKSAVSAVGKRKGPDPLSDGPVCKRPALLPSHFVTSPQTPTPGESMEDVRHSESKLDSSAALLQNIINIKNECNPVSLNTVQVSWMSPTVPQNSPRDQCQDFHGGQAFSPPQKYQPFQVSGSPQMMDQASMYQYSPQTQNMQQPPPLPPQQQHQQNYPHNSPLQFSPYSRMSQSPKYDSNLFDTHEPQFCTGQSFVSLLTGPGEPESLAVPVPAPTSIPPQTETQLQTFSLMPSNACEAVVGVHDVGSHSLGTSLSLQNIMGSPMNTTQLGKSFFQWQVEQEESKLANIPQDQFLARDGDGDTFLHIAVAQGRRALSYVLARKMNALHMLDIKEHNGQSAFQVAVAANQHLIVQDLVNLGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVRSNQFVDLEATNYDGLTPLHCAVVAHNAVVHELQRNRQSHSPEVQDLLLRNKSLVDTIKCLIQMGAAVEAKDRKSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRVTQLDAVRLLMRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRAPPY
Tissue specificity：Expressed in kidney, liver, lung and heart. Expressed at very low levels in skeletal muscle, spleen and brain. {ECO:0000269|PubMed:11356851}.
Induction：By IL-1, LPS, peptidoglycan, bacterial lipoprotein, flagellin, MALP-2, R-848 and CpG DNA, but not by TNF-alpha. {ECO:0000269|PubMed:11086164, ECO:0000269|PubMed:11278262, ECO:0000269|PubMed:11356851, ECO:0000269|PubMed:15241416}.
Developmental stage：
Protein families：