PCAT2_MOUSE Q8BYI6
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UniProt:Q8BYI6
Recommended name：Lysophosphatidylcholine acyltransferase 2
EC number：EC 2.3.1.23
Alternative names：(LPC acyltransferase 2) (LPCAT-2) (LysoPC acyltransferase 2) (1-acylglycerol-3-phosphate O-acyltransferase 11) (1-AGP acyltransferase 11) (1-AGPAT 11) (1-acylglycerophosphocholine O-acyltransferase) (1-alkenylglycerophosphocholine O-acyltransferase) (1-alkylglycerophosphocholine O-acetyltransferase) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 1)
Cleaved into：
GeneID：270084
Gene names (primary )：Lpcat2
Gene names (synonym )：Aytl1 Aytl1a Lpcat2a
Gene names (ORF )：
Length：544
Mass：60254
Sequence：MNRCAEAAAVAATVPGSGVGDAGLRPPMVPRQASFFPPPVPNPFVQQTTISASRRLQMFLLGIILLPVRALLVGIILLLAWPFAVISTACCPEKLTHPISNWRRKITRPALTFLARAMFFSMGFTVTVKGKVASPLEAPIFVVAPHSTFFDGIACVVAGLPSLVSRNENAQTPLVGRLLRALQPVLVSRVDPDSRKNTINEIKKRATSGGEWPQILVFPEGTCTNRSCLITFKPGAFIPGVPVQPVLLRYPNKLDTVTWTWQGYTFLQLCVLTFCQLFTKVEIEFMPVQAPSEEEKNDPVLFASRIRNLMAEALEIPVTDHTYEDCRLMISAGQLTLPMEAGLVEFSKISRKLKLDWDGIRKHLDEYASIASSSKGGRIGIEEFAEYLKLPVSDVLRQLFALFDRNNDGSIDFREYVIGLAVLCNPANTEEIIQVAFKLFDVDEDGYITEEEFCTILQASLGVPDLNVSGLFREIAQRDSVSYEEFKSFALKHPEYAKIFTTYLDLQTCHVFSLPEEVQTAPSVASNKVSPESQEEGTSDKKVD
Tissue specificity：Highest expression is found in resident macrophages and casein-induced neutrophils followed by skin, colon, spleen and thioglycollate-induced macrophages. Detected in erythroleukemic cells but not in reticulocytes. {ECO:0000269|PubMed:17182612, ECO:0000269|PubMed:18156367}.
Induction：By inflammatory stimulation by LPS and by ODN1826, a TLR9 ligand, but not by poly(I:C), a TLR3 ligand. {ECO:0000269|PubMed:17182612}.
Developmental stage：
Protein families：1-acyl-sn-glycerol-3-phosphate acyltransferase family