IRF8_MOUSE P23611
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UniProt:P23611
Recommended name:Interferon regulatory factor 8
EC number:
Alternative names:(IRF-8) (Interferon consensus sequence-binding protein) (ICSBP)
Cleaved into:
GeneID:15900
Gene names (primary ):Irf8
Gene names (synonym ):Icsbp Icsbp1
Gene names (ORF ):
Length:424
Mass:48237
Sequence:MCDRNGGRRLRQWLIEQIDSSMYPGLIWENDEKTMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFKEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQKCKLGVAPAGCMSEVPEMECGRSEIEELIKEPSVDEYMGMTKRSPSPPEACRSQILPDWWVQQPSAGLPLVTGYAAYDTHHSAFSQMVISFYYGGKLVGQATTTCLEGCRLSLSQPGLPKLYGPDGLEPVCFPTADTIPSERQRQVTRKLFGHLERGVLLHSNRKGVFVKRLCQGRVFCSGNAVVCKGRPNKLERDEVVQVFDTNQFIRELQQFYATQSRLPDSRVVLCFGEEFPDTVPLRSKLILVQVEQLYARQLVEEAGKSCGAGSLMPALEEPQPDQAFRMFPDICTSHQRPFFRENQQITV
Tissue specificity:Mainly expressed in lymphoid tissues (PubMed:2111015). Predominantly expressed in CD8(+)-expressing dendritic cells (PubMed:12393690). {ECO:0000269|PubMed:12393690, ECO:0000269|PubMed:2111015}.
Induction:By interferon gamma. {ECO:0000269|PubMed:17579016}.
Developmental stage:
Protein families:IRF family