BPI_MOUSE Q67E05
We list detailed information on various proteins on this webpage, which EnkiLife references when developing protein-related products. The protein data is sourced from UniProt, and since UniProt updates its information periodically, the data on our webpage may not always be up-to-date or may contain inaccuracies. If you notice any errors while browsing, we warmly welcome your feedback. Additionally, if you have any suggestions regarding any aspect of our website, please feel free to share them with us. As a token of our appreciation, we will offer a free product or a discount voucher for purchases to scientists who provide feedback. Please contact us at Email: order@enkilife.com; to share your feedback and get your rewards.
UniProt:Q67E05
Recommended name：Bactericidal permeability-increasing protein
EC number：
Alternative names：(BPI)
Cleaved into：
GeneID：329547
Gene names (primary )：Bpi
Gene names (synonym )：
Gene names (ORF )：
Length：483
Mass：53940
Sequence：MTWAPDNVRKWSALLLLAIIGTALTAATDPGFVAMISQKGLDFACQQGVVELQKELQAISVPDFSGVFKIKHLGKGSYEFYSMAVDGFHIPNPKIEMLPSDGLRVFIKDASIKINGKWMSRKNFLKAGGNFELSIQGVSISTDLILGSDSSGHITTICSNCDSHIDSVHIKISGSMLGWLIRLFHRKIETSLKNIIYKKICKIVRDSVSSKLQPYLKTLSVITRVDDVTSVDYSLLAPLTTTNQFLEGQLKGEFFWRGHRDPLPIHPPVMRFVPNGAYMVCMGISDYFFNTEVLAYQQSGTLKMTLGGQLLSNNGRFQLNTDFLRTFLPKVAKMFPSMGVQLLISAPVPVHLSIQPSGLSFNPKLETQAFVVLPNASLVPLFVLGMKTNASLEVDAEENRLVGEMKLGSRWLLELKESKFGPFKVEYLEDVINYLVSTLVLPKINERLRRGFPLPLPAGIRFSHFTFYPYQNFLLLEADLHLI
Tissue specificity：Expressed in testis, epididymis, and bone marrow, as well as in Sertoli and promyelocytic cell lines. Upon stimulation with different TLR ligands, it is strongly expressed in granulocytes and in bone marrow-derived dendritic cells. {ECO:0000269|PubMed:15590754, ECO:0000269|PubMed:16365446}.
Induction：By lipopolysaccharide (LPS) through TRL4-TRIF-dependent pathway. Expression in Sertoli and promyelocytic cells is enhanced several-fold by all-trans retinoic acid. {ECO:0000269|PubMed:15590754, ECO:0000269|PubMed:16365446}.
Developmental stage：
Protein families：BPI/LBP/Plunc superfamily, BPI/LBP family